Special

FBgn0004456 @ dm6

Biotype
protein_coding
Gene Symbol
mew
Description
The gene multiple edematous wings is referred to in FlyBase by the symbol Dmelmew (CG1771, FBgn0004456). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is X:13214409..13258490. Its molecular function is described by: protein heterodimerization activity; extracellular matrix binding; cell adhesion molecule binding. It is involved in the biological process described with 20 unique terms, many of which group under: cell adhesion; biological adhesion; cellular process; cell-cell adhesion; sensory perception of chemical stimulus. 46 alleles are reported. The phenotypes of these alleles manifest in: visual system; mitotic domain; organelle; dorsal branch primordium; endocuticle. The phenotypic classes of alleles include: lethal; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.
Coordinates
chrX:13214409-13258490:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
69
chrX:13239157-13239225
-
4.26
38.78
0
Exon Skipping
27
chrX:13223826-13223852
-
31.2
70.26
0
Intron Retention
4837
chrX:13220147-13224983
-
8.9
35.48
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000005884 ITGA3 1-to-3
Human hg38 ENSG00000091409 ITGA6 1-to-3
Human hg38 ENSG00000135424 ITGA7 1-to-3
Human hg19 ENSG00000005884 ITGA3 1-to-3
Human hg19 ENSG00000091409 ITGA6 1-to-3
Human hg19 ENSG00000135424 ITGA7 1-to-3
Mouse mm10 ENSMUSG00000001507 Itga3 1-to-3
Mouse mm10 ENSMUSG00000025348 Itga7 1-to-3
Mouse mm10 ENSMUSG00000027111 Itga6 1-to-3
Mouse mm9 ENSMUSG00000001507 Itga3 1-to-3
Mouse mm9 ENSMUSG00000025348 Itga7 1-to-3
Mouse mm9 ENSMUSG00000027111 Itga6 1-to-3
Rat rn6 ENSRNOG00000001518 Itga6 1-to-3
Rat rn6 ENSRNOG00000004276 Itga3 1-to-3
Rat rn6 ENSRNOG00000007905 Itga7 1-to-3
Cow bosTau6 ENSBTAG00000012897 ITGA7 1-to-3
Cow bosTau6 ENSBTAG00000017266 ITGA6 1-to-3
Cow bosTau6 ENSBTAG00000019498 ITGA3 1-to-3
Zebrafish danRer10 ENSDARG00000012824 itga3b 1-to-6
Zebrafish danRer10 ENSDARG00000037917 itga3a 1-to-6
Zebrafish danRer10 ENSDARG00000056018 itga6l 1-to-6
Zebrafish danRer10 ENSDARG00000069946 itga6b 1-to-6
Zebrafish danRer10 ENSDARG00000099348 ITGA6 (4 of 4) 1-to-6