FBgn0250789 @ dm6
Biotype
protein_coding
Gene Symbol
alpha-Spec
Description
The gene alpha Spectrin is referred to in FlyBase by the symbol Dmelalpha-Spec (CG1977, FBgn0250789). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3L:1778485..1795328. Its molecular function is described by: microtubule binding; actin binding; calcium ion binding. It is involved in the biological process described with 12 unique terms, many of which group under: synapse organization; cell communication; membrane organization; microtubule-based process; cellular component maintenance. 56 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane region; secretory vesicle; midline crossing tract; anterior-posterior subdivision of organism; postsynaptic membrane. The phenotypic classes of alleles include: phenotype; increased mortality; lethal - all die before end of larval stage; some die during larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 06-24 hour embryonic stages, during early larval stages.
Coordinates
chr3L:1778485-1795328:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000197694 | SPTAN1 | 1-to-1 |
| Human | hg19 | ENSG00000197694 | SPTAN1 | 1-to-1 |
| Mouse | mm10 | ENSMUSG00000057738 | Sptan1 | 1-to-1 |
| Mouse | mm9 | ENSMUSG00000057738 | Spna2 | 1-to-1 |
| Rat | rn6 | ENSRNOG00000015396 | Sptan1 | 1-to-1 |
| Cow | bosTau6 | ENSBTAG00000015327 | SPTAN1 | 1-to-1 |
| Chicken | galGal4 | ENSGALG00000004719 | SPTAN1 | 1-to-1 |
| Chicken | galGal3 | ENSGALG00000004719 | SPTAN1 | 1-to-1 |
| Zebrafish | danRer10 | ENSDARG00000019231 | spna2 | 1-to-1 |