Special

FBgn0265296 @ dm6

Biotype
protein_coding
Gene Symbol
Dscam2
Description
The gene Down syndrome cell adhesion molecule 2 is referred to in FlyBase by the symbol DmelDscam2 (CG42256, FBgn0265296). It is a protein_coding_gene from Dmel. It has 16 annotated transcripts and 16 polypeptides (15 unique). Gene sequence location is 3L:7159199..7189931. Its molecular function is described by: cell-cell adhesion mediator activity; identical protein binding. It is involved in the biological process described with: homophilic cell adhesion via plasma membrane adhesion molecules; neuron projection morphogenesis; dendrite self-avoidance; axon guidance. 26 alleles are reported. The phenotypes of these alleles manifest in: adult external mesothorax; mesothoracic segment; thoracic segment; adult mesothoracic segment; dorsal mesothorax. The phenotypic classes of alleles include: neuroanatomy defective; size defective; viable; partially lethal - majority die; body color defective.
Coordinates
chr3L:7159199-7189931:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
-
38.79
37.89
0
Alternative 3'ss
15
chr3L:7167149-7167163
-
61.21
37.89
0
Alternative 3'ss
0
NA
-
48.73
49.88
0
Alternative 3'ss
27
chr3L:7164850-7164876
-
51.27
49.88
0
Alternative 5'ss
0
NA
-
86.31
86.81
0
Alternative 5'ss
102
chr3L:7164248-7164349
-
13.69
86.81
0
Exon Skipping
288
chr3L:7172378-7172665
-
64.13
93.93
0
Exon Skipping
285
chr3L:7171673-7171957
-
35.2
97.65
0
Intron Retention
690
chr3L:7182688-7183377
-
6.68
54.64
0
Intron Retention
115
chr3L:7182426-7182540
-
18.25
100
0
Intron Retention
270
chr3L:7179868-7180137
-
7.55
38.32
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000143341 HMCN1 4-to-4
Human hg38 ENSG00000148357 HMCN2 4-to-4
Human hg38 ENSG00000171587 DSCAM 4-to-4
Human hg38 ENSG00000177103 DSCAML1 4-to-4
Human hg19 ENSG00000143341 HMCN1 4-to-4
Human hg19 ENSG00000148357 HMCN2 4-to-4
Human hg19 ENSG00000171587 DSCAM 4-to-4
Human hg19 ENSG00000177103 DSCAML1 4-to-4
Mouse mm10 ENSMUSG00000032087 Dscaml1 4-to-4
Mouse mm10 ENSMUSG00000050272 Dscam 4-to-4
Mouse mm10 ENSMUSG00000055632 Hmcn2 4-to-4
Mouse mm10 ENSMUSG00000066842 Hmcn1 4-to-4
Mouse mm9 ENSMUSG00000032087 Dscaml1 4-to-4
Mouse mm9 ENSMUSG00000050272 Dscam 4-to-4
Mouse mm9 ENSMUSG00000055632 Hmcn2 4-to-4
Mouse mm9 ENSMUSG00000066842 Hmcn1 4-to-4
Cow bosTau6 ENSBTAG00000002319 HMCN2 4-to-4
Cow bosTau6 ENSBTAG00000004754 DSCAM 4-to-4
Cow bosTau6 ENSBTAG00000015235 HMCN1 4-to-4
Cow bosTau6 ENSBTAG00000016692 DSCAML1 4-to-4
Chicken galGal4 ENSGALG00000007314 DSCAML1 4-to-3
Chicken galGal4 ENSGALG00000016138 DSCAM 4-to-3
Chicken galGal3 ENSGALG00000007314 DSCAML1 4-to-3
Chicken galGal3 ENSGALG00000016138 DSCAM 4-to-3
Zebrafish danRer10 ENSDARG00000016936 hmcn1 4-to-6
Zebrafish danRer10 ENSDARG00000024865 dscama 4-to-6
Zebrafish danRer10 ENSDARG00000028118 dscamb 4-to-6
Zebrafish danRer10 ENSDARG00000079327 hmcn2 4-to-6
Zebrafish danRer10 ENSDARG00000098057 dscaml1 4-to-6