BtaEX0022567 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000015962 | MMADHC
Description
Bos taurus methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria (MMADHC), mRNA. [Source:RefSeq mRNA;Acc:NM_001034541]
Coordinates
chr2:46648517-46655819:+
Coord C1 exon
chr2:46648517-46648568
Coord A exon
chr2:46652246-46652390
Coord C2 exon
chr2:46655602-46655819
Length
145 bp
Sequences
Splice sites
3' ss Seq
GGGTTTTGTGTCATTCTTAGGTG
3' ss Score
9.15
5' ss Seq
TCTGTAAGT
5' ss Score
7.96
Exon sequences
Seq C1 exon
GGGAAGAGTACGGCCCTGGGAGCGCTGGAGGCGGCTGTGGCGGCCGCGACTG
Seq A exon
GTGCTCTGTAACAGAGCCAGACTGATTTCCTATCTCCCAGGATTTTGCTCTTTAGTTAAAAGGGTTGTCAATCCCAGAGCCTTTTCAACTGCAGGATCTTCAGGTTCTGATGAGTCTCATGTGGCCACTGCACCTCCAGATATCT
Seq C2 exon
GCTCTCGAACGGTTTGGCCTGATGAAACTATGGGACCATTTGGACCTCAGGATCAGAGATTCCAGCTTCCTGGGAACATAGGTTTTGACTGTCACCTCAACGGGACGGCATCACAGAAGAAAAGCCAGGTTCATAAAACTTTACCTGATGTTCTAGCAGAACCTTTATCGAGTGAAAGACATGAGTTTGTTATGGCACAATATGTGAATGAATTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000015962_MULTIEX1-2/8=C1-4
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.184 C2=0.205
Domain overlap (PFAM):
C1:
NA
A:
PF102294=DUF2246=PU(11.6=65.3)
C2:
PF102294=DUF2246=FE(26.1=100),PF133151=DUF4085=PU(14.4=21.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGAGTACGGCCCTGGGAG
R:
TGTGCCATAACAAACTCATGTCT
Band lengths:
249-394
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development