MmuEX6101169 @ mm10
Exon Skipping
Gene
ENSMUSG00000026766 | Mmadhc
Description
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria [Source:MGI Symbol;Acc:MGI:1923786]
Coordinates
chr2:50291285-50296309:-
Coord C1 exon
chr2:50296252-50296309
Coord A exon
chr2:50292809-50292953
Coord C2 exon
chr2:50291285-50291502
Length
145 bp
Sequences
Splice sites
3' ss Seq
AATTTCTCTGTTATTATTAGGTG
3' ss Score
7.37
5' ss Seq
TATGTAAGT
5' ss Score
6.69
Exon sequences
Seq C1 exon
GGATACTTTGCAGTGGGGCAAGAATTTGCGTCCGCCTTCTTCACTAGAAATGGCCCAT
Seq A exon
GTGCTCTGTAACAGAGCCAGACTGGTTTCCTATCTCCCAGGATTTTGTTCTTTAGTGAAAAGAGTCATCAATCCAAGAGCCTTTTCAACTGCAGGATCTTCAGGTTCTGATGAGTCTCATGTGGCCACCGCACCTCCAGATATAT
Seq C2 exon
GCTCTCGAACAGTGTGGCCTGATGAAACTATGGGACCCTTTGGACCTCAGGACCAGAGATTCCAGCTTCCTGGGAATATAGGCTTCGATTGTCACCTCAATGGGACTGCCTCACAGAAGAAAAGCCAGGCCCATAAAACTTTGCCTGATGTTCTAGCAGAGCCTCTTTCAACTGAAAGACACGAGTTTGTGATGGCGCAGTATGTAAATGAGTTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026766-'3-8,'3-4,6-8
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.347 C2=0.267
Domain overlap (PFAM):
C1:
NO
A:
PF102294=DUF2246=PU(11.6=65.3)
C2:
PF102294=DUF2246=FE(26.1=100),PF133151=DUF4085=PU(14.4=21.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGAATTTGCGTCCGCCTTC
R:
TACTGCGCCATCACAAACTCG
Band lengths:
242-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types