RnoEX0054911 @ rn6
Exon Skipping
Gene
ENSRNOG00000004740 | Mmadhc
Description
methylmalonic aciduria and homocystinuria, cblD type [Source:RGD Symbol;Acc:1303272]
Coordinates
chr3:35795872-35801038:-
Coord C1 exon
chr3:35800982-35801038
Coord A exon
chr3:35797564-35797708
Coord C2 exon
chr3:35795872-35796089
Length
145 bp
Sequences
Splice sites
3' ss Seq
GTCAATTTCTCTGTTATTAGGTG
3' ss Score
7.41
5' ss Seq
TATGTAAGT
5' ss Score
6.69
Exon sequences
Seq C1 exon
GGATACTTTGCAGAGGGGAAAAGTCTGCGTCCGCCTTCTTCACTAGAAATGGCCCAT
Seq A exon
GTGCTCTGTAACAGAGCCAGACTGGTTTCCTATCTCCCAGGATTTTGTTCTCTAGTGAAAAGAGTTATCAATCCAAGAGCCTTTTCAACTGCAGGATCGTCAGGTTCCGATGAGTCTCACGTGGCCACTGCACCTCCAGATATAT
Seq C2 exon
GCTCTCGGACAGTGTGGCCTGATGAAACCATGGGACCCTTTGGACCTCAGGACCAGAGATTCCAGCTTCCTGGGAATATAGGCTTCGATTGTCACCTCAATGGGACAGCCTCACAGAAGAAAAGCCAGGCCCATAAAACCTTGCCTGATGTTCTAGCAGAGCCTCTTTCAACCGAAAGGCACGAGTTTGTGATGGCCCAGTATGTGAATGAGTTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000004740-'5-4,'5-3,9-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.337 C2=0.281
Domain overlap (PFAM):
C1:
NO
A:
PF102294=DUF2246=PU(11.6=65.3)
C2:
PF102294=DUF2246=FE(26.1=100)
Main Skipping Isoform:
ENSRNOT00000066058fB8812
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGAGGGGAAAAGTCTGCGTC
R:
TACTGGGCCATCACAAACTCG
Band lengths:
249-394
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]