MmuEX6101169 @ mm9
Exon Skipping
Gene
ENSMUSG00000026766 | Mmadhc
Description
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria [Source:MGI Symbol;Acc:MGI:1923786]
Coordinates
chr2:50146805-50151829:-
Coord C1 exon
chr2:50151772-50151829
Coord A exon
chr2:50148329-50148473
Coord C2 exon
chr2:50146805-50147022
Length
145 bp
Sequences
Splice sites
3' ss Seq
AATTTCTCTGTTATTATTAGGTG
3' ss Score
7.37
5' ss Seq
TATGTAAGT
5' ss Score
6.69
Exon sequences
Seq C1 exon
GGATACTTTGCAGTGGGGCAAGAATTTGCGTCCGCCTTCTTCACTAGAAATGGCCCAT
Seq A exon
GTGCTCTGTAACAGAGCCAGACTGGTTTCCTATCTCCCAGGATTTTGTTCTTTAGTGAAAAGAGTCATCAATCCAAGAGCCTTTTCAACTGCAGGATCTTCAGGTTCTGATGAGTCTCATGTGGCCACCGCACCTCCAGATATAT
Seq C2 exon
GCTCTCGAACAGTGTGGCCTGATGAAACTATGGGACCCTTTGGACCTCAGGACCAGAGATTCCAGCTTCCTGGGAATATAGGCTTCGATTGTCACCTCAATGGGACTGCCTCACAGAAGAAAAGCCAGGCCCATAAAACTTTGCCTGATGTTCTAGCAGAGCCTCTTTCAACTGAAAGACACGAGTTTGTGATGGCGCAGTATGTAAATGAGTTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026766-'3-7,'3-3,4-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.347 C2=0.267
Domain overlap (PFAM):
C1:
NO
A:
PF102294=DUF2246=PU(11.6=65.3)
C2:
PF102294=DUF2246=FE(36.0=100),PF133151=DUF4085=PU(15.2=23.3),PF106444=Misat_Tub_SegII=PU(15.5=20.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGAATTTGCGTCCGCCTTC
R:
TACTGCGCCATCACAAACTCG
Band lengths:
242-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: