BtaEX6003558 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000012798 | KCNH8
Description
potassium channel, voltage gated eag related subfamily H, member 8 [Source:HGNC Symbol;Acc:HGNC:18864]
Coordinates
chr1:138637274-138644553:+
Coord C1 exon
chr1:138637274-138637312
Coord A exon
chr1:138641960-138642312
Coord C2 exon
chr1:138644447-138644553
Length
353 bp
Sequences
Splice sites
3' ss Seq
TGTGTCATCCTCTGGTTCAGTTG
3' ss Score
7.59
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
Exon sequences
Seq C1 exon
GTGATATCAAGATTATCAAACAAATCGACAGTCTCACAG
Seq A exon
TTGGAGCCCAAGGGAAATGGCAGCATCAAGAAGAGACTGCCGTCCATCGTGGAAGACGAGGAGGAGGAGGACGAGGGGGAGGAGACAGCCTCCCTGTCCCCCGTCTACACCAGGGGACCCGCCTCTTCTCGCAGCAAGCGGCCTGGAGGCAGTAAGAGCTACCTCGGCTTAAGCCTGAAGCAGCTGGCCTCGGGAACTGTGCCGTTTCACTCACCTATCAGAGTCTCCAGTTCAAACTCCCCCAAAACCAAGCAGGAGACGGATGCCCCAAACTATGGCAAAAGAAAAGAGAAGAACTTGAAATTGCAGCTTTCGACTTTGAACAGAGCTGGACCCCCAGACCTCAGTCCAAG
Seq C2 exon
GATTGTTGATGGAATTGAAGATGGAAACAGCAGTGAAGAAAGCCAGACTTTTGACTTTGGCTCTGACCGAGTCAGACCGGAGCCCAGAATTTCTCCTCCTCCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000012798-'18-24,'18-22,20-24=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.538 A=0.915 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 27453045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation. ELM ID: ELMI003176; ELM sequence: LPSIVE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]