BtaEX6089417 @ bosTau6

Exon Skipping

Gene

Description

Bos taurus integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3), mRNA. [Source:RefSeq mRNA;Acc:NM_001206490]

Coordinates

chr19:47019293-47027388:+

Coord C1 exon

chr19:47019293-47019412

Coord A exon

chr19:47025702-47025868

Coord C2 exon

chr19:47027323-47027388

Length

167 bp

Sequences

Splice sites

3' ss Seq

TCTGTGCTCTCTCCTGATAGAGT

3' ss Score

10.21

5' ss Seq

ACTGTAAGA

5' ss Score

4.8

Exon sequences

Seq C1 exon

AGGACACTGGCAAGGATGCTGTGAATTGTACCTACAAGAATGAGGATGACTGTGTTGTCAGATTCCAGTACTACGAAGACTCCAGTGGAAAGTCCATTTTGTATGTGGTGGAAGAGCCAG

Seq A exon

AGTGTCCCAAGGGCCCTGACATCCTGGTGGTCTTGCTATCCGTGATGGGGGCCATTCTGCTCATCGGCCTTGCGACTCTGCTCATCTGGAAGCTCCTCATCACCATCCATGACCGGAAGGAGTTTGCTAAATTTGAAGAAGAGAGAGCCAGAGCCAAATGGGACACT

Seq C2 exon

GCCAACAACCCACTGTATAAAGAGGCTACATCCACCTTCACCAACATCACCTACAGGGGCACTTAA

VastDB Features

Vast-tools module Information

Secondary ID

ENSBTAG00000009987-'21-18,'21-17,22-18=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (No Ref, Alt. Stop)

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.000 C2=0.000

Domain overlap (PFAM):

C1:

PF079657=Integrin_B_tail=FE(47.1=100)

A:

PF079657=Integrin_B_tail=PD(7.1=10.7),PF087256=Integrin_b_cyt=PU(53.2=44.6)

C2:

PF087256=Integrin_b_cyt=PD(42.6=90.9)

Main Inclusion Isoform:

ENSBTAP00000013173

Main Skipping Isoform:

NA

Other Inclusion Isoforms:

NA

Other Skipping Isoforms:

NA

Associated events

Conservation

Human

(hg38)

chr17:47307471-47307637

HIGH PSI

HsaEX6023258

(ITGB3)

Human

(hg19)

chr17:45384837-45385003

HIGH PSI

HsaEX6023258

(ITGB3)

Mouse

(mm10)

chr11:104665466-104665632

HIGH PSI

MmuEX0024668

(Itgb3)

Mouse

(mm9)

chr11:104526780-104526946

HIGH PSI

MmuEX0024668

(Itgb3)

Rat

(rn6)

chr10:92781317-92781483

HIGH PSI

RnoEX6050026

(Itgb3)

Chicken

(galGal4)

chr27:2317660-2317826

HIGH PSI

GgaEX0000331

(ITGB3)

Chicken

(galGal3)

chr27:2223048-2223214

HIGH PSI

GgaEX0000331

(F1NS08_CHICK)

Zebrafish

(danRer10)

chr12:26369105-26369271

HIGH PSI

DreEX6069518

(itgb3b)

Fruitfly

(dm6)

No conservation detected

Primers PCR

Suggestions for RT-PCR validation

F:

CAAGGATGCTGTGAATTGTACCT

R:

GTGCCCCTGTAGGTGATGTTG

Band lengths:

172-339

Functional annotations

(Submit an annotation)

There are 5 annotated functions for this event

PMID: 12535520

HsaEX6023258

Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT

PMID: 12606711

HsaEX6023258

Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, surface plasmon resonance. ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT

PMID: 18156175

HsaEX6023258

Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT

PMID: 18156175

HsaEX6023258

Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT

PMID: 20739287

HsaEX6023258

Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

Special

BtaEX6089417 @ bosTau6

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]