MmuEX0024668 @ mm10
Exon Skipping
Gene
ENSMUSG00000020689 | Itgb3
Description
integrin beta 3 [Source:MGI Symbol;Acc:MGI:96612]
Coordinates
chr11:104662329-104670476:+
Coord C1 exon
chr11:104662329-104662448
Coord A exon
chr11:104665466-104665632
Coord C2 exon
chr11:104667080-104670476
Length
167 bp
Sequences
Splice sites
3' ss Seq
TCTCCGTCTCTGCCTCCCAGAGT
3' ss Score
9.21
5' ss Seq
ACAGTGAGT
5' ss Score
8.34
Exon sequences
Seq C1 exon
CGGATACTGGCAAAAACGCCGTGAATTGTACCTACAAGAACGAGGATGACTGTGTCGTCAGATTCCAGTACTACGAAGACACCAGTGGGAGGGCAGTCCTCTATGTGGTGGAAGAGCCTG
Seq A exon
AGTGTCCCAAGGGTCCTGATATCCTGGTGGTCCTGCTGTCAGTGATGGGGGCCATCCTGCTCATTGGCCTTGCTACTCTGCTCATCTGGAAGCTACTCATCACTATCCATGACCGGAAGGAATTTGCTAAATTTGAGGAAGAACGAGCCAGAGCCAAGTGGGACACA
Seq C2 exon
GCAAACAACCCGCTGTATAAAGAGGCCACCTCCACCTTCACCAATATCACCTACCGGGGGACTTAATGAGACCATCTTCAGATGACGCCAGGACCGTGGGACTCTCTGCCATTATGTTTACAGAGGACATTTGTGTGTGTGTGGGTGTGTGGGTGTATGGGTGGGATTTGGGGCGTGGGTTGGGCTGGGCTGGAAGAATGTCAGTATGTGGGAATGTATCTCTCTGTGTGTACTTATGTGTGTGACGAGTGTGGGGAAATGTGTAATTTAAAACTTGTGATGTGTCTCACAGGCAGAGCTCCACAGCCTTTGTCCTCAGGGGCCCTCCCCAAAGGATTCTTCCTGCTTAGCTTGAGGGGGACTCATGATGCCCGGCAGGTGCTCATTACCTCTGAGAAGCTAGCTTGCTTTGTCAGGCCATTCTCCCAGAAGAGAAGGGCAGGGCTGAGGTTCCCCAACCCCCATTCCAGAGGAAGTGGTGTCAAGTCTTGGTTCTATAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020689_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079657=Integrin_B_tail=FE(47.1=100)
A:
PF079657=Integrin_B_tail=PD(7.1=10.7),PF087256=Integrin_b_cyt=PU(53.2=44.6)
C2:
PF087256=Integrin_b_cyt=PD(42.6=90.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGAGGATGACTGTGTCGTCA
R:
AATCCCACCCATACACCCACA
Band lengths:
249-416
Functional annotations
There are 5 annotated functions for this event
PMID: 12535520
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT
PMID: 12606711
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, surface plasmon resonance. ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
PMID: 18156175
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
PMID: 18156175
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT
PMID: 20739287
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types