RnoEX6050026 @ rn6
Exon Skipping
Gene
ENSRNOG00000048449 | Itgb3
Description
integrin subunit beta 3 [Source:RGD Symbol;Acc:628868]
Coordinates
chr10:92778271-92783410:+
Coord C1 exon
chr10:92778271-92778390
Coord A exon
chr10:92781317-92781483
Coord C2 exon
chr10:92783345-92783410
Length
167 bp
Sequences
Splice sites
3' ss Seq
TCTCCGTCTCTGTCTCCCAGAGT
3' ss Score
10.2
5' ss Seq
ACAGTGAGT
5' ss Score
8.34
Exon sequences
Seq C1 exon
CGGATACTGGCAAAAACGCGGTGAACTGTACCTACAAGAATGAGGACGACTGTGTCGTCAGATTCCAGTACTATGAAGACTCCAGTGGAAGGGCTGTCCTGTATGTGGTAGAAGAGCCTG
Seq A exon
AGTGTCCTAAGGGTCCTGATATCCTGGTGGTCCTGCTGTCAGTGATGGGGGCGATTCTGCTCATTGGCCTTGCTACTCTGCTCATCTGGAAGCTACTCATCACCATTCATGACCGGAAGGAATTTGCTAAATTTGAGGAAGAACGAGCCAGAGCCAAATGGGACACA
Seq C2 exon
GCAAACAACCCATTGTATAAAGAGGCCACCTCCACCTTCACCAATATCACCTACCGGGGGACTTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000048449-'41-31,'41-30,42-31=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079657=Integrin_B_tail=FE(51.3=100)
A:
PF079657=Integrin_B_tail=PD(7.7=10.7),PF087256=Integrin_b_cyt=PU(53.2=44.6)
C2:
PF087256=Integrin_b_cyt=PD(42.6=90.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGATACTGGCAAAAACGCG
R:
TTAAGTCCCCCGGTAGGTGAT
Band lengths:
186-353
Functional annotations
There are 5 annotated functions for this event
PMID: 12535520
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT
PMID: 12606711
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, surface plasmon resonance. ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
PMID: 18156175
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
PMID: 18156175
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT
PMID: 20739287
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]