DreEX6069518 @ danRer10
Exon Skipping
Gene
ENSDARG00000045070 | itgb3b
Description
integrin beta 3b [Source:ZFIN;Acc:ZDB-GENE-071207-2]
Coordinates
chr12:26367739-26370384:+
Coord C1 exon
chr12:26367739-26367858
Coord A exon
chr12:26369105-26369271
Coord C2 exon
chr12:26369995-26370384
Length
167 bp
Sequences
Splice sites
3' ss Seq
TTCTCTTTCATGTCCACTAGATT
3' ss Score
8.24
5' ss Seq
ACGGTCAGT
5' ss Score
8.02
Exon sequences
Seq C1 exon
TGTTCCATGATAAGAATGCAGTGAATTGCACCTATAAGGATGAGGACGACTGTGTGCAAAGGTTTCAGTACTACGAGGACAACAGTGGCAAATCCATCTTGTCTCTGGTCAAAGAGCCAG
Seq A exon
ATTGCCCTAAAGGCCCCGATATCTTGGTGGTGCTGCTGTCAGTAGCTGGTGCCATCTTATTCTTGGGTCTTGCCGCCTTGCTTATCTGGAAACTATTAATAACCATTCATGATCGGCGTGAATTTGCGAAGTTTGAGGAGGAGCGGGCACGAGCTAAGTGGGAAACG
Seq C2 exon
GGTCACAATCCCCTTTATAAAGGCGCCACGTCGACATTCACAAACATCACATATCGAGGCAAAGACTGACCGCAGAGAAAGGACTGGACAGCGCTAAAAAGACAGTGTTCTTTTTAAAAGTTTAAACGTTAAAACTTTCTTAAAGAATTATGCAAACATGAAAGAGTTGTAGATATTTTGTTGCTGTACATATGTAAAGTCAAATATGGCATCTTCATGTGGCAAGCCGTTTTAACATTTAATCTATAAACTGTTCTAATATTTATTTTCATGCAATACCCAGTTTTTGATATTAGTATTTTTTATCTTATTCATTATGTATTATATTCTAGTTCTTATTTATTAGATACTACTACTTATTAAATGGACACTATTAATAGCTATTAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000045070-'16-15,'16-14,17-15=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079657=Integrin_B_tail=FE(47.1=100)
A:
PF079657=Integrin_B_tail=PD(7.1=10.7),PF087256=Integrin_b_cyt=PU(53.2=44.6)
C2:
PF087256=Integrin_b_cyt=PD(42.6=87.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCTCTGGTCAAAGAGCCAG
R:
AAACGGCTTGCCACATGAAGA
Band lengths:
253-420
Functional annotations
There are 5 annotated functions for this event
PMID: 12535520
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT
PMID: 12606711
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, surface plasmon resonance. ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
PMID: 18156175
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
PMID: 18156175
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001559; ELM sequence: TANNPLYK; Overlap: PARTIAL_RIGHT
PMID: 20739287
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001539; ELM sequence: TANNPLY; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]