BtaEX6093577 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000016420 | CTNNB1
Description
Bos taurus catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), mRNA. [Source:RefSeq mRNA;Acc:NM_001076141]
Coordinates
chr22:13885924-13887307:+
Coord C1 exon
chr22:13885924-13886074
Coord A exon
chr22:13886162-13886283
Coord C2 exon
chr22:13887247-13887307
Length
122 bp
Sequences
Splice sites
3' ss Seq
ATTTTTCCTTCCTCTCCCAGCAA
3' ss Score
9.1
5' ss Seq
GAGGTAGGC
5' ss Score
8.99
Exon sequences
Seq C1 exon
CTGCTTTATTCTCCTATTGAAAATATCCAAAGAGTAGCTGCAGGGGTCCTCTGTGAACTTGCTCAGGACAAGGAAGCTGCAGAAGCTATTGAAGCCGAGGGAGCCACAGCTCCTCTGACAGAATTACTTCATTCTAGGAATGAAGGTGTGG
Seq A exon
CAACATATGCAGCTGCTGTTTTGTTCCGAATGTCTGAGGACAAGCCACAGGATTATAAGAAACGGCTTTCGGTTGAGCTGACCAGTTCTCTCTTCAGAACGGAGCCAATGGCTTGGAATGAG
Seq C2 exon
ACTGCTGATCTTGGACTTGATATTGGTGCCCAGGGAGAACCTCTTGGATATCGCCAGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000016420-'31-27,'31-24,32-27=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.118 A=0.024 C2=0.714
Domain overlap (PFAM):
C1:
PF0051418=Arm=PD(51.2=41.2)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGAAAATATCCAAAGAGTAGCTGCA
R:
TCCTGGCGATATCCAAGAGGT
Band lengths:
194-316
Functional annotations
There are 1 annotated functions for this event
PMID: 16476742
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, protein kinase assay, western blot. ELM ID: ELMI001503; ELM sequence: KRLSVEL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]