RnoEX6038292 @ rn6
Exon Skipping
Gene
ENSRNOG00000054172 | Ctnnb1
Description
catenin beta 1 [Source:RGD Symbol;Acc:70487]
Coordinates
chr8:129625423-129626545:+
Coord C1 exon
chr8:129625423-129625573
Coord A exon
chr8:129625694-129625815
Coord C2 exon
chr8:129626485-129626545
Length
122 bp
Sequences
Splice sites
3' ss Seq
ATTTTCTCTCTCTACTCCAGCAA
3' ss Score
9.08
5' ss Seq
GAGGTAGGC
5' ss Score
8.99
Exon sequences
Seq C1 exon
TTGCTTTATTCTCCCATTGAAAATATCCAAAGAGTAGCTGCAGGGGTCCTCTGTGAACTTGCTCAGGACAAGGAGGCTGCAGAGGCCATTGAGGCTGAGGGAGCCACAGCTCCCCTGACAGAGTTGCTCCACTCCAGGAATGAAGGCGTGG
Seq A exon
CAACATATGCGGCTGCTGTTCTATTCCGAATGTCTGAGGACAAGCCACAGGACTACAAGAAACGGCTTTCGGTTGAGCTGACCAGTTCCCTCTTCAGGACAGAGCCAATGGCTTGGAATGAG
Seq C2 exon
ACTGCTGATCTCGGACTGGACATTGGTGCCCAGGGAGAAGCCCTTGGATATCGCCAGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000054172-'18-28,'18-25,19-28=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.098 A=0.024 C2=0.238
Domain overlap (PFAM):
C1:
PF0051418=Arm=PD(51.2=41.2)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCCCATTGAAAATATCCAAAGAGT
R:
CGTCCTGGCGATATCCAAGGG
Band lengths:
203-325
Functional annotations
There are 1 annotated functions for this event
PMID: 16476742
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, protein kinase assay, western blot. ELM ID: ELMI001503; ELM sequence: KRLSVEL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]