DreEX0024848 @ danRer10
Exon Skipping
Gene
ENSDARG00000014571 | ctnnb1
Description
catenin (cadherin-associated protein), beta 1 [Source:ZFIN;Acc:ZDB-GENE-980526-362]
Coordinates
chr16:6284678-6286729:-
Coord C1 exon
chr16:6286579-6286729
Coord A exon
chr16:6285008-6285129
Coord C2 exon
chr16:6284678-6284738
Length
122 bp
Sequences
Splice sites
3' ss Seq
TTGCTATCTCTCGCCCACAGCCA
3' ss Score
9.78
5' ss Seq
GAGGTAACG
5' ss Score
9.65
Exon sequences
Seq C1 exon
TTGCTGTATTCTCCTATCGAGAACATCCAGCGTGTGGCTGCAGGAGTGCTGTGTGAACTGGCTCAGGATAAGGAGGCGGCAGAAGCCATCGAGGCAGAAGGAGCCACTGCTCCACTCACAGAGCTCCTGCACTCCAGAAACGAGGGAGTCG
Seq A exon
CCACGTACGCTGCTGCAGTTCTGTTCCGCATGTCTGAGGATAAGCCCCAGGACTACAAGAAGCGACTGTCTGTGGAGCTCACCAGCTCTCTGTTCAGAACTGAGCCCATGACCTGGAACGAG
Seq C2 exon
ACTGGAGATCTAGGGCTGGATATCGGTGCACAGGGAGAGCCTCTGGGCTACAGACAGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000014571_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.118 A=0.049 C2=0.810
Domain overlap (PFAM):
C1:
PF0051418=Arm=PD(51.2=41.2),PF0051418=Arm=PU(68.3=54.9)
A:
PF0051418=Arm=PD(29.3=29.3)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCTATCGAGAACATCCAGCG
R:
CGTCCTGTCTGTAGCCCAG
Band lengths:
202-324
Functional annotations
There are 1 annotated functions for this event
PMID: 16476742
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, protein kinase assay, western blot. ELM ID: ELMI001503; ELM sequence: KRLSVEL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]