BtaEX6110422 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000012050 | ORAI2
Description
ORAI calcium release-activated calcium modulator 2 [Source:HGNC Symbol;Acc:HGNC:21667]
Coordinates
chr25:35114124-35126594:-
Coord C1 exon
chr25:35126009-35126594
Coord A exon
chr25:35119828-35120065
Coord C2 exon
chr25:35114124-35115156
Length
238 bp
Sequences
Splice sites
3' ss Seq
AGTGTCTCTCCTGCCCCCAGCCT
3' ss Score
8.08
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
Exon sequences
Seq C1 exon
GGTCAGAAAGCAGGATATCTGAATTTAAGCAATCACACTGGGAATTCCCCAGCAGTCCAGTAGTTAGGACTCACTGCCGGGGCACAGGGTTCGGAAGTTCACAGAGGGTGATAATAAGCACTAGGCTTTAGGAGTGAATGGTCAAGGGACTGGATACACTGTCCACACCGGCTGGGAGGCCATCCTGGCTAGGAGCTGGGGAGGGAGGGAGACAGCAGGACCACAGTGTTCACGGAACAAAGGGTCACAGTGGATGAGGTCACCAGTGTGGCAGTGACCTCTGGGACATGCCTCCCAGAATTGCCTTTTTCAAATGTGGGGTGGCCGAGGCCTCAGAAAAGGTGGTGACTTGCCAGACCACCAGCCACGGGAGTGTCAGCACAGACTGGAACCCAGACCTCCCCGCCGAGCGGCTGGTACTATGCACCTTGACCTGAACCACCTCGGCTTCTGCGTAAGCCCCATGCAACAACCTGGGCACCCGAGTGGGCTCTGCAACT
Seq A exon
CCTGGCCCCCACCATGAGCACTGAGCTCAACGTGCCCGTGGACCCCTCTGCTCCTGCCTGCTCGGAACCCGGCCACAAGGGCATGGATTACCGGGACTGGGTTCGCCGCAGCTACCTGGAACTGGTCACCTCCAACCACCACTCCGTGCAGGCGCTCTCCTGGAGGAAGCTCTACCTGAGCAGGGCCAAGCTGAAGGCCTCCAGCAGGACATCCGCCCTCCTCTCAGGCTTTGCCATG
Seq C2 exon
GTGGCCATGGTGGAGGTGCAGCTGGAGACGCAATACCAGTACCCGCGGCCGCTGCTCATCGCCTTCAGCGCCTGCACCACGGTGCTGGTGGCCGTGCACCTGTTTGCCCTGCTCATTAGCACGTGCATCCTGCCCAACGTGGAGGCCGTGAGCAACATCCACAACCTCAACTCCATCAGCGAGTCCCCACACGAGCGCATGCACCCCTACATCGAGCTGGCCTGGGGCTTCTCCACCGTGCTGGGCATCCTGCTCTTCCTGGCCGAGGTGGTGCTGCTCTGCTGGATCAAGTTCCTGCCCGTGGACGCACGCCACCAGCCGGGCCCCCCGCCCGGCCCCGGCGGCCACACCGGCTGGCAGGCCGCCCTGGTGTCCACCATCATCATGGTGCCCGTGGGCCTCATCTTCGTGGTCTTCACCATCCACTTCTACCGCTCGCTGGTGCGCCATAAGACCGAGCGGCACAACCGCGAGATCGAGGAGCTGCACAAGCTCAAGGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000012050-'0-4,'0-1,7-4=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.040 C2=0.056
Domain overlap (PFAM):
C1:
NA
A:
PF078567=Orai-1=PU(17.8=45.3)
C2:
PF078567=Orai-1=PD(81.2=86.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGGTCACAGTGGATGAGGTC
R:
CTGGTATTGCGTCTCCAGCTG
Band lengths:
299-537
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]