HsaEX0044799 @ hg38
Exon Skipping
Gene
ENSG00000160991 | ORAI2
Description
ORAI calcium release-activated calcium modulator 2 [Source:HGNC Symbol;Acc:HGNC:21667]
Coordinates
chr7:102436225-102456821:+
Coord C1 exon
chr7:102436225-102436333
Coord A exon
chr7:102438944-102439181
Coord C2 exon
chr7:102446513-102456821
Length
238 bp
Sequences
Splice sites
3' ss Seq
TGTCTCTCTCCCACCCTTAGCCT
3' ss Score
8.67
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
Exon sequences
Seq C1 exon
GGAAGGAACGTCCCAGGGATGGAAGTGCTTGGATGCGGTGCTGCTGGCTGCGGATGTGCGCAAGGAGATGGGATGGAGAGCCTGAGTTGGCATTCGTATAAATGACCTG
Seq A exon
CCTGGCTCCCACCATGAGTGCTGAGCTTAACGTGCCTATCGACCCCTCTGCTCCTGCCTGCCCTGAGCCCGGCCATAAGGGCATGGATTACCGGGACTGGGTCCGCCGCAGCTACCTGGAACTGGTCACCTCTAACCACCACTCGGTACAGGCCCTGTCGTGGCGGAAGCTCTACCTGAGCAGGGCCAAGCTGAAGGCCTCCAGCAGGACCTCCGCCCTCCTCTCCGGCTTTGCCATG
Seq C2 exon
GTGGCCATGGTGGAGGTGCAGCTGGAGACGCAGTACCAGTACCCGCGGCCGCTGCTGATTGCCTTCAGCGCCTGCACCACGGTGCTGGTGGCCGTGCACCTGTTCGCCCTCCTCATCAGCACCTGCATCCTGCCCAATGTGGAGGCCGTGAGCAACATCCACAACCTGAACTCCATCAGCGAGTCCCCGCATGAGCGCATGCACCCCTACATCGAGCTGGCCTGGGGCTTCTCCACCGTGCTTGGCATCCTACTCTTCCTGGCCGAGGTGGTGCTGCTCTGCTGGATCAAGTTCCTCCCCGTGGATGCCCGGCGCCAGCCTGGCCCCCCACCTGGCCCTGGGAGTCACACGGGCTGGCAGGCCGCCCTGGTGTCCACCATCATCATGGTGCCCGTGGGCCTCATCTTCGTGGTCTTCACCATCCACTTCTACCGCTCCCTGGTGCGCCACAAAACGGAGCGCCACAACCGCGAGATCGAGGAGCTCCACAAGCTCAAGGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160991-'3-24,'3-15,6-24
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.022 C2=0.054
Domain overlap (PFAM):
C1:
NA
A:
PF078567=Orai-1=PU(17.8=45.3)
C2:
PF078567=Orai-1=PD(81.2=86.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGGGATGGAGAGCCTGAGTT
R:
TCGGCCAGGAAGAGTAGGATG
Band lengths:
308-546
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development