DmeEX6002037 @ dm6
Exon Skipping
Gene
FBgn0030407 | CG2543
Description
The gene Folylpolyglutamate synthase is referred to in FlyBase by the symbol DmelFpgs (CG2543, FBgn0030407). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:12611867..12615530. Its molecular function is described by: tetrahydrofolylpolyglutamate synthase activity; ATP binding. It is involved in the biological process described with: tetrahydrofolylpolyglutamate biosynthetic process; folic acid-containing compound biosynthetic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout the pupal period.
Coordinates
chrX:12612395-12614850:+
Coord C1 exon
chrX:12612395-12612772
Coord A exon
chrX:12613110-12613286
Coord C2 exon
chrX:12614021-12614850
Length
177 bp
Sequences
Splice sites
3' ss Seq
TAATTTCCTACCGTTTTCAGTTG
3' ss Score
7.24
5' ss Seq
AAGGTATAT
5' ss Score
7.84
Exon sequences
Seq C1 exon
ATACCACCGCTCAATCACCTGTGAGTGAAAACTACGAGTGAGCCGAAGAGCCGTTCGTCGGAGGTCTACGATTCCGGCTCTATTGATATGGCTGCTTGTCTGTTGCGCTACTTAGTTCGACAGAGTCGCAAGCCCAGATCACTGGTCGTCAGTAGAGAGAGCTCCCACTGTAGTAGAATGAGCACCTACAGTACGGTGACCAACCTCAGTACAGTGAAAATGCAGCGCATCCAGCACCTGGCGGCATTCCGATCGGGTGTTAGCCTGGCGGAACGCGTACTTAATCCACCACAGCAGAGTATTAATGGAAATCATGTCTCGGGCAATATCCAATGCAGCAGCGATAACAATAACAAGGATACAAATGCAGCCTTTGAG
Seq A exon
TTGGCCATTAAGCAGTTAAATTCCCTGCAATCGAACGATGCTGCCATAAGGAATTCAATGAGTAATTCCCGTGTGGATACCAAAGCGGATACCATTAAATATCTGGAGCGGAGTGGTCTGCCGCTGGAAACTGTAGAGCAACTGTCCTTCATCCATGTGGCCGGCACCAAGGGCAAG
Seq C2 exon
GGCTCCACCTGCGCCTTGACGGAATCTCTGCTTCGCCATCAAGGTTTCCGCACGGGATTCTTCAGTTCTCCCCACATCCTCTTCACGAACGAGCGGATACGTATCGATGGCCAGTTGTTGTCCAAGGATAAGTTCACGGAGCAGTTCTGGAAGGTCTACAACCGTCTGTGGGATCTGCGGGAACATGATCACGACATGCCCGCCTACTTTAAGTTCCTGACCATCTTGGGATTTCATGTTTTCGTCGCAGAGAATGTGGATGTGGTCGTTTTGGAAGTGGGCATCGGTGGTGAGCACGATTGTACGAATATCGTAAGAAATGTACGCACGGTGGGCATCACATCGCTGGGACTGGAGCACACGGAGCTCTTGGGACGCACACTGCCGGAAATTGCCTGGCAGAAGGCGGGCATCATCAAGACCGGATCGCATGTCTTTACCCATGTCACTCAGCCGGAATGCCTGGAGGTGATACGTCAGCGGACAAAGGAGCACTCGGC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0030407-'3-3,'3-2,4-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.260 A=0.110 C2=0.029
Domain overlap (PFAM):
C1:
NO
A:
PF082457=Mur_ligase_M=PU(3.2=10.2)
C2:
PF082457=Mur_ligase_M=PD(95.8=65.3)
Main Inclusion Isoform:
FBpp0073488
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0312046
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAATATCCAATGCAGCAGCG
R:
ATGTCGTGATCATGTTCCCGC
Band lengths:
253-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)