DmeEX6010967 @ dm6
Exon Skipping
Gene
FBgn0034012 | Hr51
Description
The gene Hormone receptor 51 is referred to in FlyBase by the symbol DmelHr51 (CG16801, FBgn0034012). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:15331325..15339384. Its molecular function is described by 6 unique terms, many of which group under: organic cyclic compound binding; binding; heterocyclic compound binding; zinc ion binding; regulatory region nucleic acid binding. It is involved in the biological process described with 13 unique terms, many of which group under: rhythmic process; metamorphosis; rhythmic behavior; brain development; regulation of neurogenesis. 25 alleles are reported. The phenotypes of these alleles manifest in: neuron projection; plasma membrane bounded cell projection; cholinergic neuron; cellular anatomical entity; thoracic segment. The phenotypic classes of alleles include: circadian rhythm defective; phenotype; increased mortality; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr2R:15333577-15337462:+
Coord C1 exon
chr2R:15333577-15333967
Coord A exon
chr2R:15336084-15336187
Coord C2 exon
chr2R:15337348-15337462
Length
104 bp
Sequences
Splice sites
3' ss Seq
GATTCTGTTTACCATTTCAGCTG
3' ss Score
8.09
5' ss Seq
ACGGTGCGT
5' ss Score
10.25
Exon sequences
Seq C1 exon
AACTCCACAGTCCGCAGCGGCATTGCTACACTCCGCCGCCGGCGCCGATGCACGGACAGGCGCCTCCACCTACATCAACGGGCGTGGCCCCGCCCACACAGCCACCGCCCCCTCATCCCGCCGCCCCAAACGTGCCCAATGGTCGATTGCTGAGCTGGAATCACAGTGCCGCTGCAGCTGCTGCGGCGGCGGCAGCCCAAGCGGCAGCCAACTCCATGAACCACTCGTCGGCGGCGGAGGGTTCATCGATGACCCGGATTAAGGGTCAGAACCTGGGCCTCATCTGCGTGGTGTGCGGCGACACCAGCTCGGGAAAGCACTACGGAATCCTAGCCTGCAATGGCTGCTCCGGATTCTTCAAACGCAGCGTGCGGCGGAAACTCATTTATCG
Seq A exon
CTGCCAGGCGGGAACGGGACGCTGTGTGGTGGACAAAGCTCATCGGAATCAATGCCAGGCCTGCAGGCTCAAGAAGTGCCTTCAAATGGGAATGAACAAGGACG
Seq C2 exon
CCGTGCAAAATGAGCGACAGCCCCGCAACACGGCCACTATACGGCCGGAGACTCTGCGGGAGATGGAGCACGGACGGGCGCTGCGAGAGGCCGCCGTGGCCGTCGGGGTTTTCGG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0034012-'1-2,'1-1,2-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.573 A=0.056 C2=0.667
Domain overlap (PFAM):
C1:
PF0010513=zf-C4=PU(52.1=28.2)
A:
PF0010513=zf-C4=PD(46.5=91.7)
C2:
NO
Main Inclusion Isoform:
FBpp0112948

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCCAACTCCATGAACCACT
R:
AGAGTCTCCGGCCGTATAGTG
Band lengths:
242-346
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)