DmeEX6019367 @ dm6
Exon Skipping
Gene
FBgn0037726 | CG9492
Description
This gene is referred to in FlyBase by the symbol DmelCG9492 (FBgn0037726). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:9651179..9674643. Its molecular function is described by: dynein intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed; ATP binding; dynein light intermediate chain binding. It is involved in the biological process described with: cilium movement; outer dynein arm assembly; microtubule-based movement; sensory perception of sound. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: auditory perception defective; neurophysiology defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed in adult male stages.
Coordinates
chr3R:9664619-9667949:-
Coord C1 exon
chr3R:9666078-9667949
Coord A exon
chr3R:9665810-9665982
Coord C2 exon
chr3R:9664619-9664774
Length
173 bp
Sequences
Splice sites
3' ss Seq
CCATATACATTGAACTTTAGTGC
3' ss Score
3.14
5' ss Seq
TCGGTAACA
5' ss Score
5.35
Exon sequences
Seq C1 exon
ATACCATACAGAACCACCTCCTCAACATATTCGACAATACCAAATCGGTGAAATTCCACGACGTGGAGTACAACAAGATGATGGCCATCATCAGCAGCGAGGGCGAGATGATCCAGCTGGACAGGGCCATTCGAGCGGAGGGCTCGGTGGAGACCTGGCTAACCCAACTGCTGGTTACGGCCCAGGCCTCGCTGCACTCGATCATCCGTACCGCCTATGCCACCATCAACGATCCCAACTTTACGCTGCTCAGCTTCCTGGAGAAGGCTCCGGCCCAGATCGGACTGCTGGGCATTCAGATGGTGTGGACTCGGGATGCCGAAATGGCACTGATGCGGGGACGCGAACGCAAGGTCATGATGGAGACCAACAACAAGTTCCTGGAGATGCTGAACACCCTCATCGACCAGACTACGCGCAATCTCACGAAGAGGGAGCGCACCAATTTCGAGACCCTGATTACGATTCATGTGCATCAGCGTGATATCTTTGATATCCTG
Seq A exon
TGCCGCATGAACATCAAGTCAGCCAACGATTTTGAGTGGCTGAAGCAGTGTCGCTTTTACTTTAAAGAGGACTTGGACAAAACTTGGATTTCGGTTACGGATGTCACATTCACCTATCAGAACGAGTATCTGGGATGCACGGATCGCTTGGTTATCACACCGCTAACAGATCG
Seq C2 exon
ATGTTACATAACTCTGGCCCAGGCACTCACCTTGTCCATGGGCGGCGCTCCATGCGGACCAGCCGGAACGGGAAAAACGGAGACTGTCAAGGATATGGGCAAGACGCTGGCCAAGTATGTGGTCGTCTTTAATTGCTCCGATCAAATGGATTACAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0037726-'15-17,'15-16,16-17=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.005 A=0.000 C2=0.038
Domain overlap (PFAM):
C1:
PF083938=DHC_N2=WD(100=66.2)
A:
PF127742=AAA_6=PU(8.2=32.8)
C2:
PF127742=AAA_6=FE(22.4=100)
Main Inclusion Isoform:
FBpp0310725
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0301056, FBpp0301057, FBpp0301058
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAGATGCTGAACACCCTCA
R:
GACGACCACATACTTGGCCAG
Band lengths:
246-419
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)