DmeEX6024039 @ dm6

Exon Skipping

Gene

FBgn0039634 | alpha-Man-Ib

Description

The gene alpha-Mannosidase class I b is referred to in FlyBase by the symbol Dmelalpha-Man-Ib (CG11874, FBgn0039634). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29109053..29112822. Its molecular function is described by: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; calcium ion binding. It is involved in the biological process described with: encapsulation of foreign target; N-glycan processing; ubiquitin-dependent ERAD pathway. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; fertile; immune response defective; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, at stages throughout the pupal period, in adult female stages.

Coordinates

chr3R:29109053-29111275:-

Coord C1 exon

chr3R:29110935-29111275

Coord A exon

chr3R:29110689-29110876

Coord C2 exon

chr3R:29109053-29110535

Length

188 bp

Sequences

Splice sites

3' ss Seq

TAAAATAAATGACTTATCAGGTT

3' ss Score

3.62

5' ss Seq

TAAGTACGT

5' ss Score

5.1

Exon sequences

Seq C1 exon

AATTCAAGGAAGGACGCGACTGGGTAGAGCAATCACTGCGCTTTGATACCAAGCGCGATGTAAACCTATTCGAGGTCACCATACGTGTCCTAGGCGGACTGCTGTCTGCATATCACCTGAGCGGCGATACAATGTTTCTGGCCAAGGCTGCGGAACTTGGCAACCGTTTACTTCCCGCCTTTCAATCGCCGTCAAATATCCCCTATTCTGATGTGAATCTCGGAGATCTTTCGGCGCACTCGCCGAAGTGGTCTCCTGATAGCTCCACCAGTGAGGTCACCACCATTCAGCTAGAGTTTCGTGATTTGAGTCGCTCTACAAACATCTCCATTTATGAACAG

Seq A exon

GTTGCTCACAAAGTAAACGAGAAGGTGCATGATCTGGAGAAGAACCATGGTTTGGTGCCCATATTCATTAACGCCAACACAGGAACATTCCGAAACTACGCCACTATCTCGCTTGGTGCTCGTGGGGACTCCTACTATGAGTACTTGCTCAAACAGTGGATTCAGACCGGCCGCAAGGATAATGATAA

Seq C2 exon

CCTTATTTTGGACTACATGCAAGCAGTCGATGGTGTTCTAACACAACTGATGCGGCGCACGCCACGCGAGCACTGGGTTTACATTGGCGAGCTGATCAATGGCAAAGACTTTAAGCCGAAAATGGATCACCTTACGTGTTATCTGCCGGGCACTTTGATTCTGGGTCACCAGAACGGAATGCCAGACTCGCACCTTATACTTGCGAGGGATTTATTGGACACATGCTATCAGACCTATATGATGAATCCCACACATTTGGCTGCTGAGATCTCGTATTTTGCGCTAACCGAAAAGGACGATCAGGACATTTATGTGAAGCCAAACGATGCCCACAACCTGTTGCGCCCGGAGTTTGTGGAGAGTCTCTATTACTTCTACTCAATAACTGGCAATCGGACATACCAGGACATGGGATGGAAAATCTTCCAGGCGTTTGAGACTCACGCTAAAGTAAATGCAGGCTACACATCGATGGGAAATGTAAAGAACACACAGAGCA

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0039634-'3-4,'3-3,4-4=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features