DreEX0006475 @ danRer10
Exon Skipping
Gene
ENSDARG00000022772 | OSBP2 (1 of 2)
Description
oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]
Coordinates
chr5:24082429-24092442:-
Coord C1 exon
chr5:24092244-24092442
Coord A exon
chr5:24084799-24084922
Coord C2 exon
chr5:24082429-24082495
Length
124 bp
Sequences
Splice sites
3' ss Seq
GTCTTGTTGTGCTTGTACAGGAG
3' ss Score
7.79
5' ss Seq
CAGGTCAGC
5' ss Score
7.16
Exon sequences
Seq C1 exon
GCATGCCGGGATTTCCTGGAGCTGGCAGAGAGCCACAGCCGCAGATGGCAGCGAGTACTTCAGCATGAGCGTGAGCAGCGCACCCACCTGGAGGAGACCATCGAGCAGCTAGCAAAGCAGCACAACAGCCTGGAGCGAGCCTGGAGAGAGGCTCCCGCGCACGCCGTTAACACACCCGATACACCCACCACCGACACAG
Seq A exon
GAGTGAGTGAAAGGCCCAGGAAAGAGGAAGCGAGTGATGAAGATGAGGATACAGAGTATTTTGATGCCATGGAGGACTCACCTGCCTTTATAACAGTGACTGCCACGGACCCCTCTCAACACAG
Seq C2 exon
GCGTTCTCAGAGTAATCTCAGCGGTGCTAGTGGAGGACAGCCCAGTGACTGGAACCAGGATGACAAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000022772-'13-12,'13-11,15-12
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.776 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTTCCTGGAGCTGGCAGAGA
R:
TGTCATCCTGGTTCCAGTCACT
Band lengths:
254-378
Functional annotations
There are 1 annotated functions for this event
PMID: 15212954
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: glutathione s tranferase tag, pull down. ELM ID: ELMI001271; ELM sequence: EDEDTEYFDAME; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]