DreEX0040340 @ danRer10
Exon Skipping
Gene
ENSDARG00000074149 | itpr1b
Description
inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]
Coordinates
chr11:35716558-35747963:-
Coord C1 exon
chr11:35747850-35747963
Coord A exon
chr11:35738007-35738077
Coord C2 exon
chr11:35716558-35716673
Length
71 bp
Sequences
Splice sites
3' ss Seq
CATGTCTCTCTTGTCTACAGTCT
3' ss Score
8.81
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
Exon sequences
Seq C1 exon
GCACGACACAAAGTGGAGCAAAATGTCGGACAAGATGTCCAGTTTCCTCCACATCGGGGACATCTGCTCCCTGTATGCGGAGGGCTCCACCAATGGATTTATCAGCACATTGGG
Seq A exon
TCTGGTGGACGACCGCTGTGTGGTACAACCTGAATCTGGAGACCTGAACAACCCTCCTAAGAAGTTTCGAG
Seq C2 exon
ACTGTCAGTTCAGGTTGTGTCCCATGAACAGATACTCGGCCCAGAAACAGTTCTGGAAAGCAGCAAAGCCTGGTGGAAACAGCACCACAGACACTGTACTACTCAACAAACTACAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074149_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.120 C2=0.000
Domain overlap (PFAM):
C1:
PF087096=Ins145_P3_rec=PU(11.9=87.1)
A:
PF087096=Ins145_P3_rec=FE(10.6=100)
C2:
PF087096=Ins145_P3_rec=FE(16.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCAGTTTCCTCCACATCGG
R:
GTGTCTGTGGTGCTGTTTCCA
Band lengths:
172-243
Functional annotations
There are 1 annotated functions for this event
PMID: 9808459
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: western blot. ELM ID: ELMI001694; ELM sequence: PPKKF; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]