DreEX0045312 @ danRer10
Exon Skipping
Gene
ENSDARG00000016085 | mbnl3
Description
muscleblind-like splicing regulator 3 [Source:ZFIN;Acc:ZDB-GENE-081002-3]
Coordinates
chr14:30658453-30673810:-
Coord C1 exon
chr14:30673660-30673810
Coord A exon
chr14:30668767-30668802
Coord C2 exon
chr14:30658453-30658547
Length
36 bp
Sequences
Splice sites
3' ss Seq
CTTTGTGCATGGTGTTGCAGGCT
3' ss Score
7.67
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
Exon sequences
Seq C1 exon
GCTCTGCCACCAGGAGCCATGCAGCAGCTACCAAAGAGACCGACCCTGGAGAAGAGCAACGGCGCTGCTGCCGTCTTCAACCCCAGCATGTTCCACTACCAGCAGGCGTTAGCCAGCATGCAGCTGCAGCAGCCAGCGTTCATTCCCACAG
Seq A exon
GCTCCGTTTTCTGCATGGCTCCATCTGGAGGCATTG
Seq C2 exon
TTCCCATGATGCACGGTGCCACCACTTCCACTGTTTCGTCGGCTACGACCCCAGTCACCAATGTTCCTTTTGCTGAATCAGCCACCTCCAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000016085_MULTIEX1-1/3=C1-3
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (disopred):
C1=0.422 A=0.692 C2=0.883
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCAACCCCAGCATGTTCCAC
R:
GAAACAGTGGAAGTGGTGGCA
Band lengths:
113-149
Functional annotations
There are 1 annotated functions for this event
PMID: 21454535
Inferred from MBNL1 ortholog: The exon 7 region enhances MBNL1-MBNL1 dimerization properties
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]