DreEX0050296 @ danRer10
Exon Skipping
Gene
ENSDARG00000057317 | nexn
Description
nexilin (F actin binding protein) [Source:ZFIN;Acc:ZDB-GENE-041114-92]
Coordinates
chr8:18491087-18497218:-
Coord C1 exon
chr8:18497027-18497218
Coord A exon
chr8:18496539-18496623
Coord C2 exon
chr8:18491087-18491287
Length
85 bp
Sequences
Splice sites
3' ss Seq
AACTGTCGGATCCTCCACAGATA
3' ss Score
7.32
5' ss Seq
CAGGTAGGG
5' ss Score
9.46
Exon sequences
Seq C1 exon
AAACTGCTCAAAACATCAAAGCCCGTACAGAGGAGTTACATTCCCAAGTTGGGGAAAGAGGATGTAAAGAACAAATTTGAGGCCATGCAGAAAGCTAGAGAAGAGAGAAACCAAAAGAGGAGTCAGGAAGAGCAGAAGAAGCGCAGAGAGCAGTACGTTAAAGAGAGAGAGTACGGCCGCAGGAAACAAATG
Seq A exon
ATAAAGGAGCTCCTTGCCTCTAGCGATGAAGAGGAAGAGGTGAAACCCACAAAGATAGAGAAATCCTATGTTCCCAAGATCACAG
Seq C2 exon
GAAGGTGATGACAGTCTTTTGGTGCGAGTGGTGCCTGCGAAATCGCAGAAACAACCAGGAAGAATCAAAATCAACTTCGAGGACATGGAGAAGAGCCGAGAAGAGGAACTAAAGAAACGAACCGAGGAGGAGAAGATGAAGCGGTATGATGAAAACCGGCGGTCCGTCCGAGAGTCTAAACGTCGCTCCGTTGTTGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057317_MULTIEX1-3/4=2-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.963 A=0.908 C2=0.973
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGCAGAAGAAGCGCAGAGAG
R:
CCTCTTCTCGGCTCTTCTCCA
Band lengths:
169-254
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]