Special

MmuEX0031537 @ mm9

Exon Skipping

Gene
ENSMUSG00000039103 | Nexn
Description
nexilin [Source:MGI Symbol;Acc:MGI:1916060]
Coordinates
chr3:151915772-151918329:-
Coord C1 exon
chr3:151918249-151918329
Coord A exon
chr3:151916015-151916093
Coord C2 exon
chr3:151915772-151915920
Length
79 bp
Sequences
Splice sites
3' ss Seq
TTACTTATTCAACCACCTAGATT
3' ss Score
4.47
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GTACAAAAATATACAAGGCTTCAGCCCCAAACCACATAACCACATATAGCAAACATGAATGACGTTTCGCAAAAGGCAGAG
Seq A exon
ATTAAAGAAATGCTTGCTTCTGATGATGAGGAAGAAAGTTCTCCTAAAATAGAAAAGGCTTATGTCCCAAAGCTAACAG
Seq C2 exon
GGACAGTTAAAGGTAAATTCGATGAAATGGAGAAACACAGACAGGAAGAACAAAGAAAGAGAACAGAAGAAGAAAGAAAACGCAGAATTGAGCAGGATCTGTTAGAAAAGAGGAAAATACAGCGCGAATTAGCAAAAAGAGCGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039103_MULTIEX2-2/2=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.833 A=1.000 C2=0.940
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000037120





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000037120f3923A
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr1:77917960-77918038 
HIGH PSI
HsaEX0042621
(NEXN)
Human
(hg19)
chr1:78383645-78383723 
HIGH PSI
HsaEX0042621
(NEXN)
Rat
(rn6)
chr2:257472520-257472595 
HIGH PSI
RnoEX0059428
(Nexn)
Cow
(bosTau6)
chr3:67029325-67029403 
HIGH PSI
BtaEX6016951
(NEXN)
Chicken
(galGal4)
chr8:17832118-17832199 
Chicken
(galGal3)
chr8:19632349-19632430 
HIGH PSI
GgaEX0013099
(NEXN)
Zebrafish
(danRer10)
chr8:18496539-18496623 
HIGH PSI
DreEX0050296
(nexn)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ATGACGTTTCGCAAAAGGCAG

				
R: 
CCGCTCTTTTTGCTAATTCGCG

				
Band lengths: 
167-246

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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