MmuEX0031537 @ mm10

Exon Skipping

Gene

ENSMUSG00000039103 | Nexn

Description

nexilin [Source:MGI Symbol;Acc:MGI:1916060]

Coordinates

chr3:152252808-152255365:-

Coord C1 exon

chr3:152255285-152255365

Coord A exon

chr3:152253051-152253129

Coord C2 exon

chr3:152252808-152252956

Length

79 bp

Sequences

Splice sites

3' ss Seq

TTACTTATTCAACCACCTAGATT

3' ss Score

4.47

5' ss Seq

CAGGTGAGA

5' ss Score

9.22

Exon sequences

Seq C1 exon

GTACAAAAATATACAAGGCTTCAGCCCCAAACCACATAACCACATATAGCAAACATGAATGACGTTTCGCAAAAGGCAGAG

Seq A exon

ATTAAAGAAATGCTTGCTTCTGATGATGAGGAAGAAAGTTCTCCTAAAATAGAAAAGGCTTATGTCCCAAAGCTAACAG

Seq C2 exon

GGACAGTTAAAGGTAAATTCGATGAAATGGAGAAACACAGACAGGAAGAACAAAGAAAGAGAACAGAAGAAGAAAGAAAACGCAGAATTGAGCAGGATCTGTTAGAAAAGAGGAAAATACAGCGCGAATTAGCAAAAAGAGCGGAGCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSMUSG00000039103-'5-13,'5-11,8-13

Average complexity

C1

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.908 A=1.000 C2=0.923

Domain overlap (PFAM):

C1:

NO

A:

NO

C2:

NO

Main Inclusion Isoform:

ENSMUSP00000037120

Main Skipping Isoform:

ENSMUSP00000142573

Other Inclusion Isoforms:

ENSMUSP00000142559, ENSMUSP00000142569, ENSMUSP00000142574, ENSMUSP00000142936, ENSMUSP00000143133, ENSMUSP00000143180, ENSMUSP00000143294, ENSMUSP00000143573

Other Skipping Isoforms:

NA

Associated events

MmuEX0031536

Other assemblies

mm9

Conservation

Human

(hg38)

chr1:77917960-77918038

HIGH PSI

HsaEX0042621

(NEXN)

Human

(hg19)

chr1:78383645-78383723

HIGH PSI

HsaEX0042621

(NEXN)

Rat

(rn6)

chr2:257472520-257472595

HIGH PSI

RnoEX0059428

(Nexn)

Cow

(bosTau6)

chr3:67029325-67029403

HIGH PSI

BtaEX6016951

(NEXN)

Chicken

(galGal4)

chr8:17832118-17832199

Chicken

(galGal3)

chr8:19632349-19632430

HIGH PSI

GgaEX0013099

(NEXN)

Zebrafish

(danRer10)

chr8:18496539-18496623

HIGH PSI

DreEX0050296

(nexn)

Fruitfly

(dm6)

No conservation detected

Primers PCR

Suggestions for RT-PCR validation

F:

ATGACGTTTCGCAAAAGGCAG

R:

CCGCTCTTTTTGCTAATTCGCG

Band lengths:

167-246

Functional annotations

(Submit an annotation)

There are 0 annotated functions for this event

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS

Pre-implantation embryo development
Ribosome-engaged transcriptomes of neuronal types
Neural differentiation time course
Muscular differentiation time course
Spermatogenesis cell types
Reprogramming of fibroblasts to iPSCs
Hematopoietic precursors and cell types

Special

MmuEX0031537 @ mm10

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS