DreEX0081645 @ danRer10
Exon Skipping
Gene
ENSDARG00000057918 | tsc1b
Description
tuberous sclerosis 1b [Source:ZFIN;Acc:ZDB-GENE-030131-3404]
Coordinates
chr21:17290446-17296119:+
Coord C1 exon
chr21:17290446-17291037
Coord A exon
chr21:17294032-17294075
Coord C2 exon
chr21:17295953-17296119
Length
44 bp
Sequences
Splice sites
3' ss Seq
ATATCTGCAATCGCTCTCAGACT
3' ss Score
6.22
5' ss Seq
GAGGTAAAC
5' ss Score
7.2
Exon sequences
Seq C1 exon
GAGACCCTGACTGGAGCACAACAGAAACCCCTGCCCTCCTCTATTCTTCACAACACCATCTCCACCCCTGACAAAACTGAAATAACACCCAGTGACAAAGGAAGAGTCAGCAGAGGCCCATCCCAAGAGCAACCCTGGTCCTTCCAGCCAGTGTTCATGCCCATCGAACACCCGACGCACAGCCTCCTTCATCGGAGCCCGTCAGCACCAGATGACGAGGCCTTAAAATTTGGCTTGTGTTCCCCGAGCCCATGCAAACCTCCACCCATGCCATACGAGGCTCTGTTTGACATGGCTCTGCCTCGGGCTGCCTCTCTTTTTGTGGGAAGGAAGACTTCAGAGATTGTGCAGCGAGTGGCGATGGAGAGGTTTCAGAGAGGGGATTCTGGCAGGCAAGGGGAGGACGAGGGTGTGGAGGGGGTCGCCTCTGCTTCGCCTCTGGAGGTGCTGGATCGCCTCGTGCAGCAGGGTGGAGACGCCCATGACAAAGTGCTAAAGAG
Seq A exon
ACTGCCCCTGCCAAGCAAGTCAGCTGACTGGACACACTTTGGAG
Seq C2 exon
GTTCAGCTCCTCTGGATGAGTTGCACACACTGCGCAGTCAGCTTCTGCTTCTACACAACCAGCTCCTGTATGAGCGCTATAAGCGAGAGCAGCACGCCGTTCGCAACCGACGTCTGCTTAGGCGAATCATCAACGCCACTGCACTCGAGGAGCAGAATAATGCTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057918-'14-18,'14-17,16-18
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.740 A=0.062 C2=0.054
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(26.1=100)
A:
PF043887=Hamartin=FE(2.0=100)
C2:
PF043887=Hamartin=PD(5.0=67.9)
Main Skipping Isoform:
ENSDART00000145057fB6851
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACGCCCATGACAAAGTGCTA
R:
CCTAAGCAGACGTCGGTTGC
Band lengths:
148-192
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]