MmuEX6100014 @ mm9
Exon Skipping
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28531520-28534638:+
Coord C1 exon
chr2:28531520-28532078
Coord A exon
chr2:28533682-28533725
Coord C2 exon
chr2:28534472-28534638
Length
44 bp
Sequences
Splice sites
3' ss Seq
CCTGTGAAATCTTTTCCTAGGTT
3' ss Score
8.38
5' ss Seq
GAGGTAACG
5' ss Score
9.65
Exon sequences
Seq C1 exon
CGAGGGGGCTTTGACTCTCCCTTCTACCGAGACAGTCTCTCTGGCTCTCAGCGGAAGACTCATTCGGCAGCCTCTGGGACTCAGGGCTCCAGCGTGAACCCTGAGCCTTTGCACTCCTCCCTGGACAAACATGGGCCTGACACACCAAAGCAAGCCTTTACTCCCATAGACCCACCCTCTGGCAGTGCTGATGTCAGTCCCGCTGGGGACAGGGATCGCCAGACTTCTCTGGAGACCAGTATCCTCACTCCCAGCCCTTGCAAAATCCCACCTCAGAGGGGAGTGAGCTTTGGAAGTGGGCAGCTTCCCCCATATGATCATCTCTTTGAGGTGGCCTTGCCAAAGACTGCCTGTCACTTTGTCAGCAAGAAGACTGAGGAGCTGTTGAAGAAAGTGAAAGGAAACCCTGAGGAAGACTGTGTGCCCTCTACCTCCCCAATGGAAGTACTGGACAGACTGATAGAGCAGGGAGCAGGTGCGCACAGCAAGGAGCTGAGCAG
Seq A exon
GTTGTCCCTGCCCAGCAAGTCTGTTGACTGGACCCACTTTGGAG
Seq C2 exon
GCTCTCCTCCCTCAGATGAGCTCCGGACCCTCCGAGACCAGTTGCTTTTACTGCACAATCAGCTGCTGTACGAGCGCTTCAAGCGGCAGCAGCATGCACTCAGGAACAGAAGGCTCCTGCGCAAGGTGATCCGAGCAGCGGCTCTGGAGGAACACAATGCAGCAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812-'28-27,'28-26,29-27=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.787 A=0.300 C2=0.086
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(26.1=100)
A:
PF043887=Hamartin=FE(2.1=100)
C2:
PF043887=Hamartin=PD(5.3=67.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGACTGTGTGCCCTCTACCTC
R:
AAAAGCAACTGGTCTCGGAGG
Band lengths:
136-180
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: