DreEX6011362 @ danRer10
Exon Skipping
Gene
ENSDARG00000026048 | tsc1a
Description
tuberous sclerosis 1a [Source:ZFIN;Acc:ZDB-GENE-030131-9111]
Coordinates
chr5:29060076-29060597:+
Coord C1 exon
chr5:29060076-29060238
Coord A exon
chr5:29060330-29060442
Coord C2 exon
chr5:29060540-29060597
Length
113 bp
Sequences
Splice sites
3' ss Seq
AGGGGTTATTTTTGTTGCAGGGG
3' ss Score
6.41
5' ss Seq
AAGGTGCAT
5' ss Score
4.62
Exon sequences
Seq C1 exon
AGTGATGAGGTCAAATCCTCAGGGATGAAGGAGGAGCTGTGGAGCCCTTCCTCCATATGTGGGATGAGCACCCCTCCCAGTTCTAGAGGAATGTCCCCAACCACAGTTTCTGACATCTCACTTAGTGCCTCACACCTCTCAGGACGGATCCCCAGCACCCCAG
Seq A exon
GGGATGGAAAGTGGACTCTATCTCCCACCACACCCTCGGGGTCATCCCCTCTCCCATCGCTCTCAGAGGAAATAGGGCAGGCTGCCCAAAACACCAGCAGTACCCAGGCTAAG
Seq C2 exon
ACGTGCAAAGAGGTGAAGAAAGTCACATCCAGAAGTATTAATAACAGCAGTGAGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000026048-'15-16,'15-15,16-16=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.964 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(7.8=100)
A:
PF043887=Hamartin=FE(5.4=100)
C2:
PF043887=Hamartin=FE(2.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTCAGGGATGAAGGAGG
R:
CTCACTGCTGTTATTAATACTTCTGG
Band lengths:
202-315
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]