MmuEX6100018 @ mm10
Exon Skipping
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28672393-28675248:+
Coord C1 exon
chr2:28672393-28672504
Coord A exon
chr2:28672785-28672903
Coord C2 exon
chr2:28675188-28675248
Length
119 bp
Sequences
Splice sites
3' ss Seq
TTGTCCTTGTCTCTGAGCAGGTG
3' ss Score
8.95
5' ss Seq
AAGGTGGGA
5' ss Score
6.03
Exon sequences
Seq C1 exon
GCTAGTCTCTGGAGCCCATCTGCGGTCTGTGGTATGACCACTCCTCCTACGTCTCCTGGAAATGTCCCAGCTGATTTGTCACATCCGTATAGTAAAGCCTTTGGTACCACTG
Seq A exon
GTGGAAAAGGAACTCCTTCAGGAACCCCAGCGACCTCTCCTCCTCCAGCCCCACCTTGTCCCCAAGATGACTGTGTGCATGGTTCAGCAGCCCAGGCCTCAGCCACAGCCCCCAGGAAG
Seq C2 exon
GAAGAAAGAGCAGATTCCTCAAGGCCTTACCTTCACAGACAGTCAAACGACCGAGGATTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812-'21-29,'21-27,27-29=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.892 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(5.2=100)
A:
PF043887=Hamartin=FE(5.5=100)
C2:
PF043887=Hamartin=FE(2.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAGTCTCTGGAGCCCATCTGC
R:
CTAATCCTCGGTCGTTTGACT
Band lengths:
171-290
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types