DreEX6083918 @ danRer10
Exon Skipping
Gene
ENSDARG00000057918 | tsc1b
Description
tuberous sclerosis 1b [Source:ZFIN;Acc:ZDB-GENE-030131-3404]
Coordinates
chr21:17285693-17288838:+
Coord C1 exon
chr21:17285693-17285858
Coord A exon
chr21:17285978-17286096
Coord C2 exon
chr21:17288742-17288838
Length
119 bp
Sequences
Splice sites
3' ss Seq
TTTTGCTGGTTCTCATGCAGCAG
3' ss Score
7.33
5' ss Seq
AAGGTACTC
5' ss Score
7.46
Exon sequences
Seq C1 exon
AACTCCAGCTGTGAATTTAATGCCACATATGGGGTTAAGGATTCTCTCTGGAGCCCCTCCTCCCAGTGTGGGATGGCCACTCCCCCTTCCTCCCGTGGGATGTCACCAAACCCGGAACTGTCCCAGAGTGCCTCTCACCTACCGAGCCGCCTCTACAGCACACCTG
Seq A exon
CAGGTGGAAAAGGCACCCCGTCCTCCAGCACGCCTGCAGCTGCAACACCTCCTCCTAGTCTATCAGATGAGTATCCCCCTGTATCGACGCCACGCAGCACCGCCAGCCCACCATGCAAG
Seq C2 exon
GATGGTAGACCTTTAGACCATATTAAACCGGTCTTGGTCAGACAAGAGCAACTCAGAGAGTCTGAAAAAACTGGGCCTGAAACGATGAATCACAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057918-'10-13,'10-11,11-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.786 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(7.3=100)
A:
PF043887=Hamartin=FE(5.2=100)
C2:
PF043887=Hamartin=FE(4.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGCTGTGAATTTAATGCCACA
R:
TCATCGTTTCAGGCCCAGTTT
Band lengths:
250-369
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]