DreEX6020802 @ danRer10
Exon Skipping
Gene
ENSDARG00000074723 | myo10l1
Description
myosin X-like 1 [Source:ZFIN;Acc:ZDB-GENE-080425-1]
Coordinates
chr6:10893459-10901103:-
Coord C1 exon
chr6:10900997-10901103
Coord A exon
chr6:10897703-10897970
Coord C2 exon
chr6:10893459-10894244
Length
268 bp
Sequences
Splice sites
3' ss Seq
TGACATGACACTCATTACAGAAA
3' ss Score
5.12
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
GTTTTCCTAAAGGAAACCCTGGAACAGAAGCTGGAGAAGCAGAGAGATGAAGTGCGAAGCAAAGCTGGCCTGATCATACGAGCATACCTTCTAAGATATATTGCAAG
Seq A exon
AAAGGACTTTAAGAAGGCTCTGGAGAGCATTGTGACCATCCAGAAGAACTACCGCACTCATCTCTATCGACGGAGGTTTCAGCGGAAACGCTCTGCTGCGCTGGTCCTTCAGAAGCACAGGAGAGGGCAAGTGGCAAGAGGAGTCTGCCGTAAACTACGAGACGAGAAGAAGAAGAGAGAGGAGGAGGAAAGGAAAAAGAAAGAGGAGCAGGAGAAGAAAACAGAGGGAGATCGTGAAAAGAAAAATGAAGAGGAAGACGAGGCTGAG
Seq C2 exon
TCTCCACGCACTGTTGAGGAGGATACCCGCCAGATGGAGGAAATCTTGCGTTTGGAGCGAGAGATTGAGATTCTGCAGAAGAAAAGAGAAGACAGTGTGTCCACGCTTTGTGAGAGCTCCAAACAGGAACTCCGCTTGCGCCGTGATGCCGAGGTCCTGCGACAGAAAAAAGCAGCATCTCGTGTGGCCACTGAATTCCTTGAACTCCTTGACACTGGAGGCCCTGAAGTCATCCCTGGGGATCCTAAACAAGCTGCTTCCAGATCGGCAACAGCCACTGAGGAAGAGGTAGACGAAGGCTTTCACGCAGAGGAAGAGTGCATACCACTTCCAGAGTTCCCTCCGCCAGCAGAAGGTCCAGTGGATCAGGAGATCTTAGCCACTTTACCGCCTCCTCCTGCTGCATTCGCTGAGGGCACGGTGGCTCCATCAGCACCCAACGTTCCACCTGGAGCTCCTCCTCCACCTTCTCCTCCTCCACCTCCTCCTCTTCCTGGCGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074723-'22-25,'22-24,23-25=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.433 C2=0.908
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(1.2=8.3)
A:
PF0061222=IQ=WD(100=23.3)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCAAAGCTGGCCTGATCA
R:
GCTTGTTTAGGATCCCCAGGG
Band lengths:
306-574
Functional annotations
There are 2 annotated functions for this event
PMID: 20731332
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: comigration in gel electrophoresis, competition binding. ELM ID: ELMI001883; ELM sequence: LYCVVIIQKNYRAFLLRRRF; Overlap: FULL
PMID: 20731332
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: comigration in gel electrophoresis, competition binding. ELM ID: ELMI001884; ELM sequence: KKAAIVFQKQLRGQIARRVY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]