RnoEX6009019 @ rn6
Exon Skipping
Gene
ENSRNOG00000010161 | Myo10
Description
myosin X [Source:RGD Symbol;Acc:1307193]
Coordinates
chr2:78036058-78038131:+
Coord C1 exon
chr2:78036058-78036164
Coord A exon
chr2:78037348-78037575
Coord C2 exon
chr2:78038083-78038131
Length
228 bp
Sequences
Splice sites
3' ss Seq
CGGCCACTCTTCTTTTGCAGAAA
3' ss Score
10.64
5' ss Seq
AAGGTATGT
5' ss Score
9.79
Exon sequences
Seq C1 exon
GTCTTCCTTCGGGAATCCTTGGAGCAGAAACTGGAGAAGAGGCGGGAAGAGGAGATTGACCGGGCAGCCATGGTCATCCGAGCTCACATCTTAGGCTACTTGGCACG
Seq A exon
AAAGCAATATAGAAAAGTCCTTTGTGGTGTGGTGACCATACAGAAGAATTACAGAGCTTTCCTCGCGAGGAAGAGATTTCTGCACCTGAAAAAGGCAGCCATCGTGTTCCAGAAGCAGCTCCGAGGACGGCTGGCACGCAAGGTTTACAGGCAGCTTTTGGCCGAGAAACGGGAGCTGGAGGAGAGGAAGAGGTTGGAGGAAGAGAAGAAGAGAGAGGAAGAAGAAAG
Seq C2 exon
AGAAAGAAAGCGAGCACAAAGAGAAGCTGACCTCCTCCGTGCCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010161-'39-35,'39-34,40-35=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.169 C2=0.647
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.7=8.3),PF0061222=IQ=PU(76.2=44.4)
A:
PF0061222=IQ=PD(19.0=5.2),PF0061222=IQ=WD(100=26.0),PF0061222=IQ=WD(100=27.3)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTTCGGGAATCCTTGGAGC
R:
CTGGGCACGGAGGAGGTC
Band lengths:
149-377
Functional annotations
There are 2 annotated functions for this event
PMID: 20731332
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: comigration in gel electrophoresis, competition binding. ELM ID: ELMI001883; ELM sequence: LYCVVIIQKNYRAFLLRRRF; Overlap: FULL
PMID: 20731332
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: comigration in gel electrophoresis, competition binding. ELM ID: ELMI001884; ELM sequence: KKAAIVFQKQLRGQIARRVY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]