DreEX6026192 @ danRer10
Exon Skipping
Gene
ENSDARG00000075962 | vav3b
Description
vav 3 guanine nucleotide exchange factor b [Source:ZFIN;Acc:ZDB-GENE-070912-251]
Coordinates
chr2:16382769-16386355:-
Coord C1 exon
chr2:16386264-16386355
Coord A exon
chr2:16383113-16383135
Coord C2 exon
chr2:16382769-16382802
Length
23 bp
Sequences
Splice sites
3' ss Seq
TCTGTCTCATCATGATTTAGGTG
3' ss Score
9.6
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GGGGATTTTTAACCAAGGCTACCTTTGTCCTAAATGTGGAAACGGGGCTCATAAGGGCTGTCTGGGTAAACTGGGAGTCTGTGGAAGGACAG
Seq A exon
GTGCTGCAGTTCAGAAACCACAG
Seq C2 exon
AGAAAGACAACACCTAGAAAACAAGAAGACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000075962-'17-19,'17-18,18-19=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.537 C2=1.000
Domain overlap (PFAM):
C1:
PF0013017=C1_1=PD(56.9=93.5),PF144461=Prok-RING_1=FE(55.6=100),PF0063014=Filamin=PU(0.7=3.2)
A:
PF144461=Prok-RING_1=FE(14.8=100),PF0063014=Filamin=FE(5.4=100)
C2:
PF144461=Prok-RING_1=PD(1.9=8.3),PF0063014=Filamin=FE(7.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACCAAGGCTACCTTTGTCCT
R:
TGGGTCTTCTTGTTTTCTAGGTGT
Band lengths:
115-138
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]