Special

MmuEX0051295 @ mm10

Exon Skipping

Gene
Description
vav 3 oncogene [Source:MGI Symbol;Acc:MGI:1888518]
Coordinates
chr3:109563104-109578364:+
Coord C1 exon
chr3:109563104-109563204
Coord A exon
chr3:109574106-109574131
Coord C2 exon
chr3:109578319-109578364
Length
26 bp
Sequences
Splice sites
3' ss Seq
AATTTTTACCTTTGTTTCAGAAC
3' ss Score
9.11
5' ss Seq
GAGGTAAGA
5' ss Score
10.06
Exon sequences
Seq C1 exon
GGGAACATTTTATCAAGGCTACTTATGTTTTAAGTGTGGAGCAAAAGCACATAAAGAATGTTTGGGAAGAGTAGACAATTGTGGCAGAGTTAATTCCGTTG
Seq A exon
AACAAGGGCCATTCAAACCACCAGAG
Seq C2 exon
AAACGGACCAATGGACTTCGGAGAGCTTCCAGACAGGTGGACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033721-'32-34,'32-32,38-34
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.086 A=0.920 C2=0.787
Domain overlap (PFAM):

C1:
PF0063014=Filamin=FE(14.0=100),PF0013017=C1_1=PD(58.5=88.6)
A:
PF0063014=Filamin=FE(3.3=100)
C2:
PF0063014=Filamin=PU(6.5=56.2)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGTGTGGAGCAAAAGCACAT
R:
GTCCACCTGTCTGGAAGCTCT
Band lengths:
112-138
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types