DreEX6026379 @ danRer10
Exon Skipping
Gene
ENSDARG00000100494 | pbx1a
Description
pre-B-cell leukemia homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-000405-1]
Coordinates
chr2:19073365-19078840:-
Coord C1 exon
chr2:19078650-19078840
Coord A exon
chr2:19076596-19076731
Coord C2 exon
chr2:19073365-19073524
Length
136 bp
Sequences
Splice sites
3' ss Seq
CTTCTGTCATTTTCCATTAGACG
3' ss Score
6.26
5' ss Seq
CAGGTGAAC
5' ss Score
5.56
Exon sequences
Seq C1 exon
GCGTGTAATGAGTTCACCACCCATGTGATGAACCTGCTGAGGGAGCAGTCTCGCACCCGGCCCATCTCCCCCAAAGAGATAGAGCGCATGGTGAGCATCATCCACCGCAAGTTCAGCTCCATCCAAATGCAGCTCAAACAGAGCACCTGCGAGGCGGTCATGATCCTGCGCTCCCGCTTCCTCGACGCAAG
Seq A exon
ACGAAAAAGGAGAAACTTCAACAAGCAGGCCACAGAGATCCTGAATGAATACTTTTATTCCCATCTCAGCAACCCTTACCCCAGCGAGGAGGCCAAGGAGGAGTTAGCAAAGAAATGCTCAATTACAGTCTCACAG
Seq C2 exon
GTATCCAACTGGTTTGGAAACAAAAGGATCAGATACAAGAAAAATATTGGAAAATTCCAAGAAGAAGCCAACATGTACGCTGCCAGAACCGCCGCTAACGCAACCAGCGTCTCCACCCACGGCAGCCAAGCCAACTCGCCTTCCACACCAAATTCGGCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000100494-'7-12,'7-9,8-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.219 A=0.022 C2=0.463
Domain overlap (PFAM):
C1:
PF037928=PBC=PD(30.8=95.3),PF070286=DUF1319=PD(43.7=81.2),PF040917=Sec15=PD(67.1=82.8),PF0004624=Homeobox=PU(0.1=0.0)
A:
PF0004624=Homeobox=PU(75.0=97.8)
C2:
PF0004624=Homeobox=PD(21.7=24.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGATGAACCTGCTGAGGGA
R:
TTCTGGCAGCGTACATGTTGG
Band lengths:
256-392
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]