HsaEX6034601 @ hg19

Exon Skipping

Gene

ENSG00000185630 | PBX1

Description

pre-B-cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:8632]

Coordinates

chr1:164768936-164781386:+

Coord C1 exon

chr1:164768936-164769126

Coord A exon

chr1:164776779-164776914

Coord C2 exon

chr1:164781227-164781386

Length

136 bp

Sequences

Splice sites

3' ss Seq

TTTCCTTTCTCTTTACAAAGGCG

3' ss Score

8.02

5' ss Seq

CAGGTAAGC

5' ss Score

9.88

Exon sequences

Seq C1 exon

GCCTGCAACGAGTTCACCACCCACGTGATGAATCTCCTGCGAGAGCAAAGCCGGACCAGGCCCATCTCCCCAAAGGAGATTGAGCGGATGGTCAGCATCATCCACCGCAAGTTCAGCTCCATCCAGATGCAGCTCAAGCAGAGCACGTGCGAGGCGGTGATGATCCTGCGTTCCCGATTTCTGGATGCGCG

Seq A exon

GCGGAAGAGACGGAATTTCAACAAGCAAGCGACAGAAATCCTGAATGAATATTTCTATTCCCATCTCAGCAACCCTTACCCCAGTGAGGAAGCCAAAGAGGAGTTAGCCAAGAAGTGTGGCATCACAGTCTCCCAG

Seq C2 exon

GTATCAAACTGGTTTGGAAATAAGCGAATCCGGTACAAGAAGAACATAGGTAAATTTCAAGAGGAAGCCAATATTTATGCTGCCAAAACAGCTGTCACTGCTACCAATGTGTCAGCCCATGGAAGCCAAGCTAACTCGCCCTCAACTCCCAACTCGGCTG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000185630-'17-22,'17-21,18-22=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.219 A=0.022 C2=0.333

Domain overlap (PFAM):

C1:

PF037928=PBC=PD(48.0=95.3),PF090686=EF-hand_2=PD(65.9=93.8),PF059039=Peptidase_C97=PD(60.3=73.4),PF070286=DUF1319=PD(60.7=79.7),PF040917=Sec15=PD(59.2=65.6)

A:

PF0157913=DUF19=FE(27.3=100),PF0004624=Homeobox=PU(91.8=97.8)

C2:

PF0004624=Homeobox=PD(21.7=24.1)

Main Inclusion Isoform:

ENSP00000405890f9298A