MmuEX0033848 @ mm9
Exon Skipping
Gene
ENSMUSG00000052534 | Pbx1
Description
pre B cell leukemia homeobox 1 [Source:MGI Symbol;Acc:MGI:97495]
Coordinates
chr1:170121409-170133668:-
Coord C1 exon
chr1:170133478-170133668
Coord A exon
chr1:170125879-170126014
Coord C2 exon
chr1:170121409-170121568
Length
136 bp
Sequences
Splice sites
3' ss Seq
TTCCCTTTCTTGTTCTGAAGGCG
3' ss Score
7.92
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GCATGCAATGAATTCACCACCCACGTGATGAACCTCCTTCGAGAGCAAAGCCGGACCAGGCCCATCTCTCCGAAGGAGATCGAGCGGATGGTGAGCATCATCCACCGCAAGTTCAGCTCCATCCAGATGCAGCTGAAACAGAGCACGTGCGAGGCCGTCATGATCCTGCGCTCCCGGTTCCTGGATGCGAG
Seq A exon
GCGGAAGAGACGGAATTTCAACAAGCAAGCCACAGAAATTCTGAATGAATATTTCTATTCCCATCTCAGCAACCCTTACCCCAGTGAGGAAGCCAAAGAGGAGTTAGCCAAGAAGTGCGGCATCACAGTCTCCCAG
Seq C2 exon
GTATCAAACTGGTTTGGAAATAAGCGAATCCGGTACAAGAAGAACATAGGTAAATTTCAAGAGGAAGCCAATATTTATGCTGCCAAAACGGCTGTCACAGCCACCAATGTGTCAGCCCATGGAAGCCAAGCTAACTCGCCCTCTACTCCCAACTCAGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000052534-'5-8,'5-7,6-8
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.214 A=0.022 C2=0.333
Domain overlap (PFAM):
C1:
PF037928=PBC=PD(30.8=95.3),PF070286=DUF1319=PD(54.2=81.2),PF040917=Sec15=PD(64.6=82.8),PF0157913=DUF19=FE(38.2=100),PF0004624=Homeobox=PU(0.1=0.0)
A:
PF0157913=DUF19=FE(27.3=100),PF0004624=Homeobox=PU(91.8=97.8)
C2:
PF0044324=UCH=PD(23.0=77.8),PF0004624=Homeobox=PD(21.7=24.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGGTGAGCATCATCCACCG
R:
GCGAGTTAGCTTGGCTTCCAT
Band lengths:
244-380
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types