DreEX6027967 @ danRer10

Exon Skipping

Gene

ENSDARG00000068288 | lamc2

Description

laminin, gamma 2 [Source:ZFIN;Acc:ZDB-GENE-110222-3]

Coordinates

chr2:36025210-36029462:+

Coord C1 exon

chr2:36025210-36025346

Coord A exon

chr2:36029009-36029165

Coord C2 exon

chr2:36029257-36029462

Length

157 bp

Sequences

Splice sites

3' ss Seq

TTTATCATGTGTTTTTTTAGATA

3' ss Score

10.39

5' ss Seq

CAAGTAGGA

5' ss Score

4.46

Exon sequences

Seq C1 exon

CTTGTAACTGCAACCGACAGGGTTCTGTGTCCAATTCATGCAGTGATAAAGGCCAGTGCGAGTGTAAGGAAGGATATGATGGACTTAGGTGTGAAGAATCAACATGTCCATCCTGCTTTAATCCAGTTAAGAGCAAG

Seq A exon

ATAGAGGTCTATGCACGCCAGCTGCAGGAAATGGAGGATTTATTTAAGGGATTTGGAGGTAATGAAGCTCCGGTCAGCGATGCTCAGATGGACCAGGCTGTTCGGGCAGCAGAAGTCATGGTCCGAAACCTGGAGAGCAGAGCAAACGAACTCACAA

Seq C2 exon

ACACGGAGAAACAGCTTCAGGATAAACTGGCGAGCATTAGCCGATCTCAGCTGAGGGAGGATAGAAACATGGAGGCTTTGTTGACAAGCGTGAATGGGATCAGAAACAATGATCAACAGTACAGGACAGAAGTTTCCGAAATCCGTAAACTCATCAGTGACGTCAGGTCAAAGCTGCAGCAGGCCAAACGGGACATGCAGGAGATT

VastDB Features

Vast-tools module Information

Secondary ID

ENSDARG00000068288-'12-13,'12-12,13-13=AN

Average complexity

A_S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.500 C2=0.464

Domain overlap (PFAM):

C1:

PF059116=DUF869=FE(23.4=100),PF0005319=Laminin_EGF=WD(100=97.8),PF131661=AAA_13=PU(23.9=84.8),PF059296=Phage_GPO=PU(9.1=26.1),PF041117=APG6=PU(8.8=26.1)

A:

PF059116=DUF869=FE(27.1=100),PF0005319=Laminin_EGF=PD(0.1=0.0),PF131661=AAA_13=FE(31.9=100),PF059296=Phage_GPO=FE(39.4=100),PF041117=APG6=FE(38.2=100),PF060137=WXG100=PU(75.0=96.2),PF045827=Reo_sigmaC=PU(25.5=67.9),PF078897=DUF1664=PU(30.2=54.7),PF097894=DUF2353=PU(18.0=45.3)

C2:

PF059116=DUF869=FE(35.4=100),PF131661=AAA_13=FE(41.7=100),PF059296=Phage_GPO=PD(50.0=95.7),PF041117=APG6=FE(50.0=100),PF060137=WXG100=PD(22.1=21.7),PF045827=Reo_sigmaC=FE(48.2=100),PF078897=DUF1664=PD(67.7=94.2),PF097894=DUF2353=FE(51.1=100)

Main Inclusion Isoform:

ENSDARP00000089477