DreEX6053838 @ danRer10
Exon Skipping
Gene
ENSDARG00000061736 | ank3a
Description
ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]
Coordinates
chr17:20713831-20722938:-
Coord C1 exon
chr17:20722906-20722938
Coord A exon
chr17:20714204-20714428
Coord C2 exon
chr17:20713831-20713985
Length
225 bp
Sequences
Splice sites
3' ss Seq
TCTTTCTTCTCTTCTTGCAGGTT
3' ss Score
13.17
5' ss Seq
AGGGTACGA
5' ss Score
7.38
Exon sequences
Seq C1 exon
CCCTTCCTCCCCGCTTCCTCAGTATGACTCCAG
Seq A exon
GTTCCTAGTGAGTTTTATGGTGGATGCTCGGGGCGGGTCGATGAGAGGAAGTCGTCACGATGGTATGCGCATAATCGTTCCACCCAGAAAGTGTCCAGCACCGACACGAATCACCTGTCGTTTAGCAAAGCGCCACCGCCTGGCATACCCACCACCTATGGTGGAGGGAGAGGGTCTTGTGAGCAGACTGGTGGAAATGGGGCCAGCTGGGGCACAGTTTTTAGG
Seq C2 exon
ACCTGTGATAGTAGAAATTCCCCATTTTGGCTCCATGCGGGGAAAGGAGAGAGAGCTAATCGTCTTACGCAGTGATAATGGGGAGACCTGGAAAGAACATCATTATGACTGCAAAGTGACAGAGCTCACCTCAATCCTCAATGGCATGGACGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000061736-'36-38,'36-37,37-38=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.167 A=0.171 C2=0.094
Domain overlap (PFAM):
C1:
PF0079115=ZU5=PU(1.0=8.3)
A:
PF0079115=ZU5=FE(71.4=100)
C2:
PF0079115=ZU5=PD(26.7=52.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTTCCTCCCCGCTTCC
R:
CTTCGTCCATGCCATTGAGGA
Band lengths:
188-413
Functional annotations
There are 1 annotated functions for this event
PMID: 26024478
The paper describes and annotates all exons to an extreme detail. Wild-type isoform, but not the variants (either skipping 31 or 28-31), bind beta-spectrin. Exon 28 (MmuEX0004926), exon 29 (MmuEX6048924), exon 31 (MmuEX6048923)
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]