MmuEX6048923 @ mm9
Exon Skipping
Gene
ENSMUSG00000069601 | Ank3
Description
ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]
Coordinates
chr10:69413700-69421820:+
Coord C1 exon
chr10:69413700-69413806
Coord A exon
chr10:69418674-69418898
Coord C2 exon
chr10:69421666-69421820
Length
225 bp
Sequences
Splice sites
3' ss Seq
CTTTTTCCAACCCCGCACAGGTT
3' ss Score
7.61
5' ss Seq
AGGGTAAGT
5' ss Score
10.45
Exon sequences
Seq C1 exon
CACCTGACGTTCACGAGGGAGTTTGATTCTGACTCCCTCAGACACTACAGTTGGGCAGCGGACACGTTAGATAATGTGAACCTGGTCTCAAGCCCGGTGCATTCTGG
Seq A exon
GTTTCTGGTTAGCTTTATGGTGGACGCGAGAGGGGGCTCCATGCGAGGAAGCCGCCACCACGGGATGCGGATCATCATCCCTCCGCGAAAGTGTACGGCCCCCACCCGCATCACGTGCCGCCTGGTAAAGAGACATAAACTGGCCAACCCACCCCCCATGGTGGAAGGAGAGGGATTAGCCAGTAGGCTGGTAGAAATGGGTCCTGCGGGGGCACAATTTTTAGG
Seq C2 exon
CCCCGTCATTGTGGAAATCCCTCATTTTGGGTCCATGAGGGGGAAGGAGAGAGAACTTATCGTCCTTCGGAGCGAGAACGGAGAGACCTGGAAGGAACATCAGTTTGACAGTAAAAACGAAGACCTCGCGGAGCTTCTCAATGGCATGGATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069601-'32-37,'32-35,34-37=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.011 A=0.218 C2=0.303
Domain overlap (PFAM):
C1:
PF0079115=ZU5=PU(1.0=2.8)
A:
PF0079115=ZU5=FE(89.3=100),PF0079115=ZU5=PU(0.1=0.0)
C2:
PF0079115=ZU5=PD(26.7=52.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
ENSMUSP00000045834, ENSMUSP00000061698, ENSMUSP00000090087, ENSMUSP00000090088, ENSMUSP00000090089, ENSMUSP00000090090, ENSMUSP00000090090f5390A, ENSMUSP00000090090f5391A, ENSMUSP00000090090f5392A, ENSMUSP00000090090f5393A, ENSMUSP00000090090f5394A, ENSMUSP00000090090f6290A, ENSMUSP00000090090f6291A
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTGACGTTCACGAGGGAG
R:
TCATCCATGCCATTGAGAAGCT
Band lengths:
260-485
Functional annotations
There are 1 annotated functions for this event
PMID: 26024478
The paper describes and annotates all exons to an extreme detail. Wild-type isoform, but not the variants (either skipping 31 or 28-31), bind beta-spectrin. Exon 28 (MmuEX0004926), exon 29 (MmuEX6048924), exon 31 (MmuEX6048923)
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: