RnoEX0009368 @ rn6
Exon Skipping
Gene
ENSRNOG00000053288 | Ank3
Description
ankyrin 3 [Source:RGD Symbol;Acc:620157]
Coordinates
chr20:20403689-20411476:+
Coord C1 exon
chr20:20403689-20403795
Coord A exon
chr20:20408425-20408649
Coord C2 exon
chr20:20411322-20411476
Length
225 bp
Sequences
Splice sites
3' ss Seq
GTCTGATCTTCTCCCTACAGGTT
3' ss Score
11.87
5' ss Seq
AGGGTAAGT
5' ss Score
10.45
Exon sequences
Seq C1 exon
CACCTTCCATTCACGAGGGAGTTTGACTCCGACTCCCTCAGACACTACAGTTGGGCAGCAGACACACTGGACAATGTGAACCTGGTCTCCAGCCCTGTGCATTCTGG
Seq A exon
GTTTCTGGTTAGCTTTATGGTGGACGCGAGAGGGGGCTCCATGCGAGGAAGCCGCCACCACGGGATGCGGATCATCATCCCTCCGCGCAAGTGTACGGCCCCCACCCGCATCACTTGCCGCCTGGTAAAGAGACATAAACTGGCCAACCCACCCCCCATGGTGGAAGGAGAGGGATTAGCCAGTAGGCTGGTAGAAATGGGTCCTGCGGGGGCACAATTTTTAGG
Seq C2 exon
CCCGGTCATAGTGGAAATCCCTCATTTTGGGTCCATGAGAGGAAAGGAGAGGGAACTCATTGTCCTCCGGAGCGAGAACGGAGAGACCTGGAAGGAACACCAGTTTGACAGCAAAAACGAAGACCTCTCGGAGCTCCTCAATGGCATGGACGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000053288-'52-61,'52-58,57-61
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=0.218 C2=0.337
Domain overlap (PFAM):
C1:
PF0079115=ZU5=PU(1.0=2.8)
A:
PF0079115=ZU5=FE(71.4=100)
C2:
PF0079115=ZU5=PD(26.7=52.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTTCCATTCACGAGGGAGT
R:
TTCGTCCATGCCATTGAGGAG
Band lengths:
260-485
Functional annotations
There are 1 annotated functions for this event
PMID: 26024478
The paper describes and annotates all exons to an extreme detail. Wild-type isoform, but not the variants (either skipping 31 or 28-31), bind beta-spectrin. Exon 28 (MmuEX0004926), exon 29 (MmuEX6048924), exon 31 (MmuEX6048923)
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]