DreEX6067865 @ danRer10
Exon Skipping
Gene
ENSDARG00000077582 | ank3b
Description
ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2]
Coordinates
chr12:7644242-7654513:-
Coord C1 exon
chr12:7654407-7654513
Coord A exon
chr12:7650280-7650504
Coord C2 exon
chr12:7644242-7644396
Length
225 bp
Sequences
Splice sites
3' ss Seq
AAATTGTTTGCCTCTTGCAGGTT
3' ss Score
9.05
5' ss Seq
GGGGTAGGT
5' ss Score
6.59
Exon sequences
Seq C1 exon
CACCTGGCCTTAGCGAAAGATTACAACACGGACTCAATGAGACGTTACAGCTGGACGCCAGATACTATGGACAATGTGAACCTGGTCTCCAGTCCTGTCCATTCAGG
Seq A exon
GTTTTTGGTGAGCTTCATGGTGGACGCACGTGGCGGGTCGATGCGAGGAAGTCGCCACAATGGCATGCGGATCATCATCCCGCCTCGCAAATGCACTGCGCCAACACGTATCACATGCCGTCTGGTCAAGAGGCACAAGCTGGCGTCGCTGCCACCCATGGTGGAGGGAGAGGGCCTGGCGAGCAGGCTGGTGGAGGTGGGCCCAGCAGGGGCTCAGTTTCTGGG
Seq C2 exon
CCCCGTGATTGTGGAGATCCCTCATTTTGGGTCCATGAGAGGGAAAGAGCGAGAACTCATTATGCTCAGGAGCGAAAACGGTGAGACCTGGAAGGAGCATCATTACGACTGCAAAACTGAAGACCTCAATGAGCTACTCAATGGCATGGATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000077582-'40-37,'40-35,42-37=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.087 A=0.096 C2=0.189
Domain overlap (PFAM):
C1:
PF0079115=ZU5=PU(1.0=2.8)
A:
PF0079115=ZU5=FE(71.4=100)
C2:
PF0079115=ZU5=PD(26.7=52.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTGGCCTTAGCGAAAGAT
R:
TCATCCATGCCATTGAGTAGCT
Band lengths:
260-485
Functional annotations
There are 1 annotated functions for this event
PMID: 26024478
The paper describes and annotates all exons to an extreme detail. Wild-type isoform, but not the variants (either skipping 31 or 28-31), bind beta-spectrin. Exon 28 (MmuEX0004926), exon 29 (MmuEX6048924), exon 31 (MmuEX6048923)
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]