DreEX6065226 @ danRer10
Exon Skipping
Gene
ENSDARG00000062686 | megf11
Description
multiple EGF-like-domains 11 [Source:ZFIN;Acc:ZDB-GENE-060503-252]
Coordinates
chr18:19252402-19259975:-
Coord C1 exon
chr18:19259729-19259975
Coord A exon
chr18:19256340-19256460
Coord C2 exon
chr18:19252402-19252538
Length
121 bp
Sequences
Splice sites
3' ss Seq
TCGCTCTTGTGGTCGGGCAGCTG
3' ss Score
5.72
5' ss Seq
ACGGTAAGA
5' ss Score
10.65
Exon sequences
Seq C1 exon
GTTGTGAAAGTGGCTACTGGGGCCCCCATTGCAGCAACCGTTGTCAGTGCAAGAATGGGGCCCTGTGTAACCCCATCACAGGGGCCTGTGTCTGCACAGACGGCTACCAAGGCTGGCGCTGTGAGGATCTGTGTGAGCCCGGCTACTATGGCAAGGGCTGCCAGCTGCAGTGTCAATGCCTCAACGGTGCCACCTGCCACCACGAGACGGGGGAATGCATATGCGCACCAGGCTACATGGGCCCCAT
Seq A exon
CTGTGGAGAGCGCTGTCCCTCTGGAAGTCACGGGCCACAGTGTGAGCAGCGATGCCCCTGTCAGAACGGAGGAACCTGCCATCACATCACTGGGGAGTGTTCCTGCCCGGCTGGATGGACG
Seq C2 exon
GGTTCTGTGTGTGCCCAGCCATGTCCGTTTGGAAAATATGGGATCAACTGCAGCAAGGAATGCTCATGCCGCAATGGAGGACTCTGTGACCACATCACAGGACAGTGTCAGTGCATGGCGGGATACAGCGGCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000062686-'4-6,'4-5,5-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=WD(100=53.5),PF126612=hEGF=PU(84.6=12.8)
A:
PF126612=hEGF=PD(7.7=2.4),PF126612=hEGF=PU(61.5=19.5)
C2:
PF126612=hEGF=PD(23.1=6.5),PF126612=hEGF=PU(84.6=23.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGTGAGGATCTGTGTGAGC
R:
CCATGCACTGACACTGTCCTG
Band lengths:
248-369
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]