HsaEX6075428 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65970553-65982488:-
Coord C1 exon
chr15:65982242-65982488
Coord A exon
chr15:65980778-65980898
Coord C2 exon
chr15:65970553-65970689
Length
121 bp
Sequences
Splice sites
3' ss Seq
ACCTCTGCTTCTCCATGCAGCTG
3' ss Score
11.47
5' ss Seq
ACGGTAAGT
5' ss Score
11.81
Exon sequences
Seq C1 exon
GCTGCGACAGCGACCACTGGGGGCCCCACTGCAGCAACCGGTGCCAGTGCCAGAACGGCGCCCTGTGTAACCCCATCACAGGCGCCTGCGTGTGCGCCGCCGGCTTCCGTGGATGGCGCTGCGAGGAGCTCTGCGCACCTGGCACCCACGGCAAGGGATGCCAGCTGCCGTGCCAGTGCCGACACGGTGCCAGCTGCGACCCCCGCGCCGGCGAGTGCCTCTGCGCACCTGGCTACACCGGCGTCTA
Seq A exon
CTGCGAGGAGCTGTGCCCTCCTGGGAGCCATGGAGCTCACTGTGAGCTGCGCTGCCCCTGTCAGAATGGGGGCACCTGCCACCACATCACTGGCGAGTGTGCCTGCCCCCCAGGCTGGACG
Seq C2 exon
GGAGCAGTGTGTGCCCAGCCCTGCCCACCAGGGACATTTGGCCAGAACTGCAGCCAGGATTGTCCTTGCCACCATGGAGGGCAGTGTGACCACGTGACTGGACAGTGCCACTGTACAGCTGGATACATGGGGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'10-29,'10-22,17-29=AN
Average complexity
A_C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.011 A=0.038 C2=0.044
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(58.1=30.1)
A:
PF0005319=Laminin_EGF=PD(39.5=41.5)
C2:
PF0005319=Laminin_EGF=PU(56.8=54.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains