RnoEX0053775 @ rn6
Exon Skipping
Gene
ENSRNOG00000010634 | Megf11
Description
multiple EGF-like-domains 11 [Source:RGD Symbol;Acc:1582797]
Coordinates
chr8:70112923-70123310:+
Coord C1 exon
chr8:70112923-70113169
Coord A exon
chr8:70114680-70114800
Coord C2 exon
chr8:70123174-70123310
Length
121 bp
Sequences
Splice sites
3' ss Seq
CGCTGTTCCTCTCGCTGCAGCTG
3' ss Score
9.61
5' ss Seq
ACGGTAGGT
5' ss Score
10.15
Exon sequences
Seq C1 exon
GCTGTGACAGCGAGCACTGGGGTCCCCACTGCAGCAACCGGTGTCAGTGTCAGAACGGCGCCTTGTGCAACCCTATCACCGGCGCCTGCGTATGCGCCCCCGGCTTCCGAGGCTGGCGCTGTGAGGAATTCTGCGCGCCCGGTACTCACGGCAAGGGCTGCCAGCTGCTCTGTCAGTGCCACCACGGCGCTAGCTGCGACCCGCGCACTGGCGAGTGCCTCTGCGCACCAGGCTACACCGGCGTTTA
Seq A exon
CTGTGAGGAGCTGTGCCCCCCTGGGAGCCATGGAGCTCACTGTGAGCTACGCTGCCCCTGCCAGAACGGAGGCACCTGCCACCACATCACTGGCGAGTGTGCCTGTCCTCCAGGCTGGACG
Seq C2 exon
GGAGCAGTGTGTGCCCAGCCCTGCCCACCAGGGACCTTTGGCCAGAACTGTAGTCAGGACTGTCCCTGCCACCATGGAGGCCAGTGTGACCATGTGACTGGACAATGCCACTGTACAGCTGGATACATGGGGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010634-'13-16,'13-15,16-16
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.052 A=0.044 C2=0.097
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=WD(100=54.2),PF0005319=Laminin_EGF=PU(54.3=30.1)
A:
PF0005319=Laminin_EGF=PD(43.5=48.8),PF126612=hEGF=PU(61.5=19.5)
C2:
PF126612=hEGF=PD(23.1=6.5),PF0005319=Laminin_EGF=PU(55.3=56.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGCGCTGTGAGGAATTCTG
R:
GGCATTGTCCAGTCACATGGT
Band lengths:
244-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]