MmuEX6066643 @ mm9
Exon Skipping
Gene
ENSMUSG00000036466 | Megf11
Description
multiple EGF-like-domains 11 [Source:MGI Symbol;Acc:MGI:1920951]
Coordinates
chr9:64486042-64495758:+
Coord C1 exon
chr9:64486042-64486288
Coord A exon
chr9:64487821-64487941
Coord C2 exon
chr9:64495622-64495758
Length
121 bp
Sequences
Splice sites
3' ss Seq
ACCTCTTCCTCTCGCTGCAGCTG
3' ss Score
11.34
5' ss Seq
ACGGTAGGT
5' ss Score
10.15
Exon sequences
Seq C1 exon
GCTGTGACAGCGAGCACTGGGGTCCCCACTGCAGCAACCGGTGTCAGTGTCAGAACGGCGCCCTGTGCAACCCTATCACCGGCGCCTGCGTGTGCGCCCCGGGCTTCCGAGGCTGGCGCTGTGAGGAACTCTGCGCTCCTGGTACTCACGGCAAGGGCTGCCAGCTGCTCTGTCAGTGCCACCATGGCGCCAGCTGTGACCCGCGCACTGGCGAGTGCCTCTGCGCTCCTGGCTACACAGGCGTTTA
Seq A exon
CTGTGAGGAGCTGTGCCCCCCTGGGAGCCATGGAGCTCACTGTGAGCTGCGCTGCCCCTGCCAGAATGGAGGCACCTGCCACCACATCACTGGCGAATGTGCCTGCCCTCCAGGCTGGACG
Seq C2 exon
GGAGCAGTGTGTGCCCAGCCCTGCCCTCCAGGGACCTTTGGCCAGAACTGTAGCCAGGACTGTCCCTGCCACCATGGAGGCCAGTGTGACCATGTGACTGGACAATGCCACTGTACAGCTGGATACATGGGGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000036466-'11-10,'11-9,12-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=WD(100=54.2),PF0005319=Laminin_EGF=PU(54.3=30.1)
A:
PF0005319=Laminin_EGF=PD(43.5=48.8),PF126612=hEGF=PU(61.5=19.5)
C2:
PF126612=hEGF=PD(23.1=6.5),PF0005319=Laminin_EGF=PU(58.1=54.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTCTGCGCTCCTGGTACTC
R:
CCAGCTGTACAGTGGCATTGT
Band lengths:
243-364
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: