DreEX6074530 @ danRer10
Exon Skipping
Gene
ENSDARG00000023472 | ctnnb2
Description
catenin, beta 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2575]
Coordinates
chr19:48335775-48338963:-
Coord C1 exon
chr19:48338914-48338963
Coord A exon
chr19:48336516-48336740
Coord C2 exon
chr19:48335775-48336028
Length
225 bp
Sequences
Splice sites
3' ss Seq
GTTCTGTGTGTGTGCTGCAGCTG
3' ss Score
9.06
5' ss Seq
CAGGTACGC
5' ss Score
10.12
Exon sequences
Seq C1 exon
GTTTGAAAGTCGCTCAGGCTAAAGGATTGACGCAACGATGGCTAGCCAGG
Seq A exon
CTGACCTGATGGAGCTGGACATGGCCATGGAGCAGGACCGTAAGGCTGCAGTGAGCCACTGGCAGCAGCAGTCCTACCTGGATTCAGGGATTCACTCGGGCGCCACCACCACTGCGCCCTCGCTCTCAGGCAAAGGAAACCCAGAGGAAGAGGATCTGGACAACCAGGTGCTGTACGAGTGGGAGCAGGGCTTCAGCCAGCCCTTCACACCTGAGCAGGTGGCAG
Seq C2 exon
ATCTGGACGGGCAGTATGCCATGACGCGGGCGCAGAGGGTTCGAGCCGCCATGTTCCCAGAGACTCTGGATGAGAGCGTCCCGATGGCCTCCACCCAGTTCGACTCTGCTCATCCAACAAACGTACAGCGTCTGGCGGAGCCGTCGCAGATGCTGAAGCATGCGGTGGTCAACCTCATCAACTACCAGGACGATGCAGAGCTCGCCACCAGAGCCATTCCAGAGCTCACCAAACTGCTGAACGACGAGGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000023472-'4-5,'4-4,7-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.400 A=0.711 C2=0.412
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF136461=HEAT_2=PU(46.1=55.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAAGTCGCTCAGGCTAAAGG
R:
GTCCTCGTCGTTCAGCAGTTT
Band lengths:
298-523
Functional annotations
There are 5 annotated functions for this event
PMID: 10074433
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI002616; ELM sequence: YLDSGIHS; Overlap: FULL
PMID: 11955436
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI002616; ELM sequence: YLDSGIHS; Overlap: FULL
PMID: 12820959
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001302; ELM sequence: DSGIHS; Overlap: FULL
PMID: 19061640
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI002616; ELM sequence: YLDSGIHS; Overlap: FULL
PMID: 12417018
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, western blot. ELM ID: ELMI002615; ELM sequence: YLDSGIHS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]