DreEX6083921 @ danRer10
Exon Skipping
Gene
ENSDARG00000057918 | tsc1b
Description
tuberous sclerosis 1b [Source:ZFIN;Acc:ZDB-GENE-030131-3404]
Coordinates
chr21:17277396-17279578:+
Coord C1 exon
chr21:17277396-17277550
Coord A exon
chr21:17279237-17279310
Coord C2 exon
chr21:17279400-17279578
Length
74 bp
Sequences
Splice sites
3' ss Seq
TGTCTGTGTTAATAATGCAGCCC
3' ss Score
5.73
5' ss Seq
CCGGTGAGA
5' ss Score
8.72
Exon sequences
Seq C1 exon
GACATGTACCAGAGGTTTATCTCATCCATCTGCACGCAAGCGTTTATTCACTTTTCCACCGGCTGTATGGGATGTACCCCTGCAATTTTGTTTCATACCTTCGCTCCCATTACAGTATGAAGGAGAACATGGATACTTTTGAGGAGGTGGTCAAG
Seq A exon
CCCATGCTTGAACATGTCAGAATACATCCTGAATTAGTGACCGGAACCAAGGACCAAGAGCTTGACCCCAGCCG
Seq C2 exon
GTGGAAGAGATTCGAAATCCACGATATAGTTATCGAGTGTGCCAAAGTCTCTCTGGACCCAAAAGAGGCGTCCTGTGAAGAGGGCTATGCCAGCATGCCTGAGCATTTCTGTGCTCATCTACAACAACGTCCGGCTGATTGCACTGCCAGTCCGTATGGTGACTTCCACAGTAGCTACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057918-'5-7,'5-6,6-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.080 C2=0.016
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(6.8=100)
A:
PF043887=Hamartin=FE(3.2=100)
C2:
PF043887=Hamartin=FE(8.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCGGCTGTATGGGATGTAC
R:
TTCACAGGACGCCTCTTTTGG
Band lengths:
178-252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]